1JOL: THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE

PDB ID: 1JOLDownload
MMDB ID: 5710
PDB Deposition Date: 1996/2/25
Updated in MMDB: 1998/11
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 1JOL: dimeric; determined by author
Molecular Components in 1JOL
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acidN-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
3
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303