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1DRB:
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
PDB ID:
1DRB
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MMDB ID:
798
PDB Deposition Date:
1991/11/6
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
1.96 Å
Source Organism:
Escherichia coli
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1DRB: dimeric; determined by author
Molecular Components in 1DRB
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Dihydrofolate Reductase
(Gene symbol:
folA
)
Chemicals and Non-standard biopolymers (7 molecules)
1
2
CHLORIDE ION
2
2
METHOTREXATE
3
2
ETHANOL
4
1
CALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303