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Conserved domains on  [gi|295414041|gb|ADG08178|]
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homeodomain protein class 2 [Encephalitozoon cuniculi]

Protein Classification

COG5576 family protein( domain architecture ID 11475647)

COG5576 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2-157 1.60e-51

Homeodomain-containing transcription factor [Transcription];


:

Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 161.45  E-value: 1.60e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295414041   2 APILPMSKLPALVSLRMNEIRGIYIETNNRVVEEMDAVIDEFAKDVGSSPDISTNVRTYLEERIRYIREFVVDHIGFSIS 81
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295414041  82 EFRTLYNPN-GNESIKSRRFPKFITEALERSFEIDQYPSEaEKARLAKICKLSTKQINNWFTNKRNRTKGHEGGRQY 157
Cdd:COG5576   81 RIKLSLLLNmPPKSVQIWFQNKRAKEKKKRSGKVEQRPGE-EEADLAKIGSLSTGQISIIETLEFSRTSYEEGGLQY 156
 
Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2-157 1.60e-51

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 161.45  E-value: 1.60e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295414041   2 APILPMSKLPALVSLRMNEIRGIYIETNNRVVEEMDAVIDEFAKDVGSSPDISTNVRTYLEERIRYIREFVVDHIGFSIS 81
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295414041  82 EFRTLYNPN-GNESIKSRRFPKFITEALERSFEIDQYPSEaEKARLAKICKLSTKQINNWFTNKRNRTKGHEGGRQY 157
Cdd:COG5576   81 RIKLSLLLNmPPKSVQIWFQNKRAKEKKKRSGKVEQRPGE-EEADLAKIGSLSTGQISIIETLEFSRTSYEEGGLQY 156
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 96-152 7.70e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 67.27  E-value: 7.70e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 295414041  96 KSRRFPKFITEALERSFEIDQYPSEAEKARLAKICKLSTKQINNWFTNKRNRTKGHE 152
Cdd:cd00086    3 KRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 96-149 5.17e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 62.65  E-value: 5.17e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 295414041    96 KSR-RFPKFITEALERSFEIDQYPSEAEKARLAKICKLSTKQINNWFTNKRNRTK 149
Cdd:smart00389   3 RKRtSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 117-147 1.08e-12

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 58.68  E-value: 1.08e-12
                          10        20        30
                  ....*....|....*....|....*....|.
gi 295414041  117 YPSEAEKARLAKICKLSTKQINNWFTNKRNR 147
Cdd:pfam05920   9 YPSEEEKAELAKETGLSRKQISNWFINARRR 39
 
Name Accession Description Interval E-value
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
2-157 1.60e-51

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 161.45  E-value: 1.60e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295414041   2 APILPMSKLPALVSLRMNEIRGIYIETNNRVVEEMDAVIDEFAKDVGSSPDISTNVRTYLEERIRYIREFVVDHIGFSIS 81
Cdd:COG5576    1 SPVQPMQPLSALESQRMPQIRTIKTTKNKREVEAADSEMKLERKQDGSSPPKSKRRRTTDEQLMVLEREFEINPYPSSIT 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295414041  82 EFRTLYNPN-GNESIKSRRFPKFITEALERSFEIDQYPSEaEKARLAKICKLSTKQINNWFTNKRNRTKGHEGGRQY 157
Cdd:COG5576   81 RIKLSLLLNmPPKSVQIWFQNKRAKEKKKRSGKVEQRPGE-EEADLAKIGSLSTGQISIIETLEFSRTSYEEGGLQY 156
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 96-152 7.70e-16

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 67.27  E-value: 7.70e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 295414041  96 KSRRFPKFITEALERSFEIDQYPSEAEKARLAKICKLSTKQINNWFTNKRNRTKGHE 152
Cdd:cd00086    3 KRTRFTPEQLEELEKEFEKNPYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 96-149 5.17e-14

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 62.65  E-value: 5.17e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 295414041    96 KSR-RFPKFITEALERSFEIDQYPSEAEKARLAKICKLSTKQINNWFTNKRNRTK 149
Cdd:smart00389   3 RKRtSFTPEQLEELEKEFQKNPYPSREEREELAKKLGLSERQVKVWFQNRRAKWK 57
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 117-147 1.08e-12

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 58.68  E-value: 1.08e-12
                          10        20        30
                  ....*....|....*....|....*....|.
gi 295414041  117 YPSEAEKARLAKICKLSTKQINNWFTNKRNR 147
Cdd:pfam05920   9 YPSEEEKAELAKETGLSRKQISNWFINARRR 39
Homeodomain pfam00046
Homeodomain;
96-149 5.72e-11

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 54.81  E-value: 5.72e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295414041   96 KSR-RFPKFITEALERSFEIDQYPSEAEKARLAKICKLSTKQINNWFTNKRNRTK 149
Cdd:pfam00046   2 RKRtTFTPEQLEELEKEFQENPYPSAEEREELAAQLGLTERQVKVWFQNRRAKWK 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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