2I0C,3KEI,2V3U,2RC7,2A5S


Conserved Protein Domain Family
Lig_chan-Glu_bd
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smart00918: Lig_chan-Glu_bd 
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Ligated ion channel L-glutamate- and glycine-binding site
This region, sometimes called the S1 domain, is the luminal domain just upstream of the first, M1, transmembrane region of transmembrane ion-channel proteins, and it binds L-glutamate and glycine. It is found in association with Lig_chan.
Links
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Statistics
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PSSM-Id: 214911
Aligned: 89 rows
Threshold Bit Score: 35.3022
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I0C_B         12 PYVLFKKSdkPLY-GN---DRFEGYCIDLLRELSTILGFTYEIRLVE---D---GKYGAQDDvNGQWNGMVRELI 76   Norway rat
XP_001650208   50 PAIFRTTH--NETdEH---LKYYGLEVELLKAISEAMKFEMDFYESD---DaavAMWGTVTD-GENATGLLGEMM 115  yellow fever mosquito
NP_197816    1445 PYLPNGDP--IPG--------FKGYAVNMIDLASE----ELDIQSSS--------GYGLRET---LFYGVFRELQ 1494 thale cress
ZP_01950628   236 PMSYWDEK--E--------KKYKGYVHDLLERISTKSILKFEFVP----------AYGRD----------VEDML 280  Vibrio cholerae 1587
YP_857513     306 PYGVRDYD-----------NQLTGMSVEMLEKISRRSGLRFEFVS-----------YGSELA-R------NEALL 351  Aeromonas hydrophi...
NP_929541     323 PYSFLDKN-----------GQITGLDVDILRLLGEKSGIIFNFIPTD-------GAVGIKKR------LEDGEAQ 373  Photorhabdus lumin...
YP_960176      33 PYNMTTNG--QPF-AHs-eSEITGLCTDVLKAVLENAKVDYSIKLRD-------LSYG------------MNRAQ 84   Marinobacter aquae...
YP_001445595  303 PYDYTQGG------------EPEGYAIDVLKIIEQSTGIKFEFIN------------G--------FNS--RQLQ 343  Vibrio harveyi ATC...
XP_316930      66 PFMIKRLS--TDG-VGnvnIRWEGLEMRLLRVMAQYLNFTYDIIEPG---R---TELGP-----G--DAVVEEIK 124  Anopheles gambiae ...
XP_317522     187 PAVFKSAT--TSN--------YYGLEIELLKAISKAMHFQMVFYETSdadK---ERWGRLGGn-GTLTGIIKEMQ 247  Anopheles gambiae ...
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