2ECW,1CHC


Conserved Protein Domain Family
zf-C3HC4
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pfam00097: zf-C3HC4 
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Zinc finger, C3HC4 type (RING finger)
The C3HC4 type zinc-finger (RING finger) is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C where X is any amino acid. Many proteins containing a RING finger play a key role in the ubiquitination pathway.
Links
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Statistics
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PSSM-Id: 395049
Aligned: 35 rows
Threshold Bit Score: 34.6379
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2ECW_A         22 CPICLELLKEPV--------SADCNHSFCRACITLNYEsnr-ntDGKGn--CPVC 65   house mouse
P32512         39 CAVCLETYCVQSnniidflmPSECTHLFCYKCVLNMYKnamnvpRAAVs--CPMC 91   Orgyia pseudotsugata multiple nucleopo...
Q06438        243 CALCGEWPTMPH--------TIGCEHVFCYYCVKSSFLf-----DMYFt--CPKC 282  Chinese hamster
P34537        785 CPSCKTRPKDc--------iMLKCYHLFCETCIKTMYD------TRQRk--CPKC 823  Caenorhabditis elegans
P32511        207 CHICSCTFTDIQnynsnfvtSTECNHAVCFKCYVSIVFg-----KESYk--CSIC 254  Orgyia pseudotsugata multiple nucleopo...
P23801         86 CSVCLETYSQQSndtcpfliPTTCDHGFCFKCVINLQSnamnipHSTVc--CPLC 138  Autographa californica nucleopolyhedro...
XP_001165648  381 CKICAENDKDVK--------IEPCGHLMCTSCLTSWQE------SEGQg--CPFC 419 
P40072        206 CPICFEPPETAL--------MTLCGHVFCCPCLFQMVNss--rtCRQFg-hCALC 249  Saccharomyces cerevisiae S288C
P32849        914 CSICTTEPMDLDka-----lFTECGHSFCEKCLFEYIEfq---nSKNLglkCPNC 960  Saccharomyces cerevisiae S288C
P36113        179 CIICCDKKDTETf-------ALECGHEYCINCYRHYIKdkl-heGNIIt--CMDC 223  Saccharomyces cerevisiae S288C
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