2CKL,5J3X,4R8P,1CHC,1JM7


Conserved Protein Domain Family
zf-C3HC4

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pfam00097: zf-C3HC4 
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Zinc finger, C3HC4 type (RING finger)
The C3HC4 type zinc-finger (RING finger) is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C where X is any amino acid. Many proteins containing a RING finger play a key role in the ubiquitination pathway.
Statistics
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PSSM-Id: 333836
View PSSM: pfam00097
Aligned: 40 rows
Threshold Bit Score: 35.4121
Threshold Setting Gi: 239938588
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
2CKL_B         57 CPICLDMLKNTMt-------TKECLHR-FCADCIITALR--------SGNKe--CPTC 96
gi 548450     243 CALCGEWPTMPH--------TIGCEHV-FCYYCVKSSFLf-------DMYFt--CPKC 282
gi 84028180   785 CPSCKTRPKDc--------iMLKCYHL-FCETCIKTMYD--------TRQRk--CPKC 823
gi 418248     207 CHICSCTFTDIQnynsnfvtSTECNHA-VCFKCYVSIVFg-------KESYk--CSIC 254
gi 1172054     86 CSVCLETYSQQSndtcpfliPTTCDHG-FCFKCVINLQSnam--nipHSTVc--CPLC 138
gi 239938588  148 CIICLTNQVQIL--------TIPCGHLiMCNPCSLNLNNsvctrgvnSNYEk--CPKC 195
gi 417587     914 CSICTTEPMDLDka-----lFTECGHS-FCEKCLFEYIEfq-----nSKNLglkCPNC 960
gi 548669     877 CPICCNEPIQNPl-------LLNCKHA-CCGDCLSEHIQyqk---rrNIIPp-lCHTC 922
gi 323308218   18 CIICCDKKDTETf-------ALECGHE-YCINCYRHYIKdkl---heGNIIt--CMDC 62
gi 768531880  206 CPICFEPPETAL--------MTLCGHV-FCCPCLFQMVNss----rtCRQFg-hCALC 249
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