1JAS,1Y6L,2O25,1AYZ,5KHR,3RCZ,2CYX,4JQU,5KNL,3ONG,5HPT,5L9T,3K9P,1Y8X,1WZV,3O2U,2Y9P


Conserved Protein Domain Family
UQ_con

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pfam00179: UQ_con 
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Ubiquitin-conjugating enzyme
Proteins destined for proteasome-mediated degradation may be ubiquitinated. Ubiquitination follows conjugation of ubiquitin to a conserved cysteine residue of UBC homologs. TSG101 is one of several UBC homologs that lacks this active site cysteine.
Statistics
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PSSM-Id: 333904
View PSSM: pfam00179
Aligned: 82 rows
Threshold Bit Score: 103.028
Threshold Setting Gi: 54035927
Created: 13-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1JAS_A   8 RLMRDFK------RLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPN-KPPTVRFLSKMFHP 79  cattle
Q64362  72 PFYLEYSllaeftLVVKQKLPGVYVQPSYr-SALVWFGVIFI-RHGLYQDGVFKFTVYIPDNYPDgDCPRLLFDIPVFHP 149 house mouse
P28263   7 RIETDVM---------KLLMSDHQVDLIND-SMQEFHVKFLGPKDTPYENGVWRLHVELPDNYPY-KSPSIGFVNKIFHP 75  Saccharomyces cerevis...
P62257  10 RMDTDVV---------KLIESKHEVTILG--GLNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPF-KSPSIGFMNKIFHP 77  house mouse
Q20617  17 RIRKEIA------DLAKNKRRFIKDFRKIEkCKDIFQFKIIG-DGVLYKNMIFTLTLDVNVEYPF-KPPYLKFCHNVYHP 88  Caenorhabditis elegans
O14933   6 RVVKELE------DLQKKPPPYLRNLSSDDaNVLVWHALLLP-DQPPYHLKAFNLRISFPPEYPF-KPPMIKFTTKIYHP 77  human
P68037   6 RLMKELE------EIRKCGMKNFRNIQVDEaNLLTWQGLIVP-DNPPYDKGAFRIEINFPAEYPF-KPPKITFKTKIYHP 77  house mouse
P52487   6 RLTRELS------DLVEAKMSTLRNIESSDeSLLMWTGLLVP-EKAPYNKGAFRIEINFPPQYPF-MPPKILFKTKIYHP 77  fruit fly
5HPT_C   5 RLMKELE------EIRKCGMKNFRNIQVDEaNLLTWQGLIV-PDNPPYDKGAFRIEINFPAEYPF-KPPKITFKTKIYHP 76  human
1WZV_A   8 RVVKELE------DLQKKPPPYLRNLSSDDaNVLVWHALLL-PDQPPYHLKAFNLRISFPPEYPF-KPPMIKFTTKIYHP 79  human
1JAS_A  80 NVY-ADGSICL-DIL-QNrWSP-TYDVSSILT-SIQSLLDEP-NPNSPANSQAAQLYQEN-KREYEKRV 141 cattle
Q64362 150 LVDpTSGELDVkRAFa--kWRRnHNHIWQVLMyARRVFY--KiDTTSPLNPEAAVLYEKDiQ-LFKSKV 213 house mouse
P28263  76 NIDiASGSICL-DVIn-StWSP-LYDLINIVEwMIPGLLKEP-NGSDPLNNEAATLQLRD-KKLYEEKI 139 Saccharomyces cerevisiae S288c
P62257  78 NIDeASGTVCL-DVIn-QtWTA-LYDLTNIFEsFLPQLLAYP-NPIDPLNGDAAAMYLHR-PEEYKQKI 141 house mouse
Q20617  89 NVDpVTCELCS-PMLlQEnWKP-ETTMEDVLL-NLIVLLNEP-DLSRPVNIDAAHDYIHN-KVEFVKKS 152 Caenorhabditis elegans
O14933  78 NVD-ENGQICL-PIIsSEnWKP-CTKTCQVLE-ALNVLVNRP-NIREPLRMDLADLLTQN-PELFRKNA 140 human
P68037  78 NID-EKGQVCL-PVIsAEnWKP-ATKTDQVIQ-SLIALVNDP-QPEHPLRADLAEEYSKD-RKKFCKNA 140 house mouse
P52487  78 NVD-EKGEVCL-PIIsTDnWKP-TTRTEQVLQ-ALVAIVHNP-EPEHPLRSDLAEEFVRE-HKKFMKTA 140 fruit fly
5HPT_C  77 NID-EKGQVCL-PVIsAEnWKP-ATKTDQVIQ-SLIALVNDP-QPEHPLRADLAEEYSKD-RKKFCKNA 139 human
1WZV_A  80 NVD-ENGQICL-PIIsSEnWKP-CTKTCQVLE-ALNVLVNRP-NIREPLRMDLADLLTQN-PELFRKNA 142 human
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