2MZ0,1Q2K


Conserved Protein Domain Family
DEFL_BmBKTx1-like
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cd21805: DEFL_BmBKTx1-like 
defensin-like domain found in Mesobuthus martensii neurotoxin BmBKTx1 and similar proteins
BmBKTx1, also called potassium channel toxin alpha-KTx 19.1, or BmK37, is a selective inhibitor of high conductance calcium-activated potassium channels KCa1.1/KCNMA1. It belongs to a family of short-chain alpha-KTx toxins of the potassium channel (also called alpha-KTx19) and may be insect specific. This subfamily also includes Arabidopsis thaliana defensin-like protein 32 (AtDEF32). Its biological function remains unclear. This model corresponds to the defensin-like (DEFL) domain of BmBKTx1 and AtDEF32, which adopts a typical structure characterized by cysteine-stabilized alpha/beta scaffold.
Links
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Statistics
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PSSM-Id: 409638
Aligned: 10 rows
Threshold Bit Score: 24.4884
Created: 31-Mar-2020
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2MZ0_A       13 TCiefPTEKCNKTCIESNFAGGKCVHigq-sldFVCVCFP 51  thale cress
1Q2K_A        2 AC---YSSDCRVKCVAMGFSSGKCIN-------SKCKCYK 31 
P83407        2 AC---YSSDCRVKCVAMGFSSGKCIN-------SKCKCYK 31  Chinese scorpion
Q2V4I8       39 TCiefPTEKCNKTCIESNFAGGKCVHigq-sldFVCVCFP 77  thale cress
NP_001031142 39 TCiefPTEKCNKTCIESNFAGGKCVHigq-sldFVCVCFP 77  thale cress
XP_002893883 39 TCvefPAERCNKTCIDSNFASGKCVHvgq-sldFVCVCYP 77  Arabidopsis lyrata subsp. lyrata
XP_006306007 34 TCvqfPIEKCIKTCIESNFAGGKCVRiggdvhdVVCVCIP 73  Capsella rubella
XP_019089110 39 SCiefPTAKCNKTCIESHFSGGTCVHvgq-sldFVCVCFF 77  false flax
XP_019094527 39 SCiefPTAKCNKTCIESHFSGGTCVHvgq-sldFVCVCFS 77  false flax
XP_022566346 56 TCy--QFPHCNQTCVESDFSGGKCVPlpparidFVCVCYP 93  rape
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