Conserved Protein Domain Family
TaR3-like_MBL-fold

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cd07715: TaR3-like_MBL-fold 
MBL-fold metallo-hydrolase domain of Myxococcus xanthus TaR3 and related proteins; MBL-fold metallo-hydrolase domain
Myxococcus xanthus Tar3 may function as an ammonium regulator/effector protein involved in biosynthesis of the antibiotic TA. Some are members of this subgroup are annotated as ribonucleases. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.
Statistics
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PSSM-Id: 293801
Aligned: 174 rows
Threshold Bit Score: 181.155
Created: 21-May-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:putative active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                            # # ##   
AAR26319    4 RFHGVRGSIAVSGs---rIGGNTACVEVTsq-ghRLILDAGTGIRALGeiMMREGap------qEATLFFSHLHWDHVQG 73  Myxococcus xanthus
EFI33785    4 VFWGARGSIPVCGpeyvrYGGETTCVEVRndqggRIILDAGTGIRRLGavLLKEQa-------lKTDLFFTHTHWDHIMG 76  Desulfonatronospir...
BAH38224   15 RFWGTRGTCASPGprtvrYGGNTPCVEVRgsggpALVLDAGTGIRCLGqhLQRSPet-----daAIHLFLTHRHADHVIG 89  Gemmatimonas auran...
EIM65205    4 KCWGSRGSICVSGqqytkYGGDTTCFEIQansgeVVIIDAGTGIRRLGksMVQKKi-------kRCYLLLTHTHWDHIIG 76  Desulfobacter post...
EMS77821    4 RCWGSRGSIAVSGrqyvaYGGDTTCLQITagsgeTVIVDAGTGIRRLGnfLLEKNi-------tRYFMLQTHCHWDHLLG 76  Desulfotignum phos...
EGJ51084    4 RFWGVRGSIPVSGkaytrFGGDSACLEVRgs-rgSVILDAGTGLRGLGnaLSAGEp-------qPIHLLLTHFHWDHILG 75  Desulfovibrio afri...
AHG90471    7 RLWGVRGSVPAPGsatrrHGGNTSCVTVRtaeghWLVLDAGTGIRAFGeeLLATTppndgrtplELTLLLTHVHWDHVQG 86  Gemmatimonadetes b...
KMQ50803    4 RCLGARGGLPVSGceflkYGGDTTCIEITadsgdLVIVDAGSGIRSLN--GSAANa-------sTINLLFTHAHLDHILG 74  haloalkaliphilic b...
ERP31280    4 ICWGVRGSLPASGrdyakYGGDTTCIEVVstkgeRLIIDSGTGIRRLSn-SLKEAds------kTVNLLLTHYHLDHIMG 76  candidate division...
CCK81490    4 KCWGSRGSISVSGekykkYGGDTTCVAVTaksgeTIIIDAGTGIRRLGnsLIKQKi-------tRYYLLFTHAHWDHILG 76  Desulfobacula tolu...
Feature 1                                                                                     
AAR26319   74 FPFFTPAWLPTSELTLYGPgangaqalqseLAAQMQPLHFPVpls-tmrSRMDFRSALHARPVEVG----PFRVTPIDv- 147 Myxococcus xanthus
EFI33785   77 LPFFQPLYQPGFSINLYGQprlqgdihrlvFKDLFRPPHFPV-------PYSRVMSQINYQEFQGGvevqGFYLETIAl- 148 Desulfonatronospir...
BAH38224   90 LPHFAPLHARTRTMHVWCGdgged-slpafLNTLVSPPLFPQvdg--lvGQLLAHEWAPGKSVAVG----EYTVHRFGa- 161 Gemmatimonas auran...
EIM65205   77 MPFFHPLLDADTTVHIQDRtfagl-ttkqvIDRVMCMPFFPVglk--ayNADIRFDSSLNNRFSIG----SLDIETILt- 148 Desulfobacter post...
EMS77821   77 FPFFKPLLHRQNQLIIQNRafgra-tlkdvFEQMMSPPFFPIrls--elQADIQFDSGLNDSFNIG----SLQIDTIPn- 148 Desulfotignum phos...
EGJ51084   76 LLFFKPLYDDRFRIAIHGPlpaee--teatLAALMRQPYFPVp-----fASVQARLSFAHLREAETv--aGFNVEAIPl- 145 Desulfovibrio afri...
AHG90471   87 LPFFAPLYDPRLRLTFGVAaavep-tvrasLQRQMCPPSFPVrld--alRSTIAFLPVADAGTRVH----DATVRPIEa- 158 Gemmatimonadetes b...
KMQ50803   75 FPFFTPLYNEEKIVNIFGYptsig-pfktvLENVMRDPLFPErfs--slSAKMSFIDIELKPFTIG----SIKISPVHl- 146 haloalkaliphilic b...
ERP31280   77 TPFIRQLFDHRYTFNIFGPclegaqtvrtpFETTISPPYFPLalenkaiQANLHFHTINETEFKIG----SLSISTIRvs 152 candidate division...
CCK81490   77 IAFFRPLQFSNVKIILQDRkfsdv-stravLAEVMKQPFFPIslk--dlRADIKFDTALNDTFTIG----SVRVETIPt- 148 Desulfobacula tolu...
Feature 1      ##                     #                                                    #
AAR26319  148 pHPQGCLAYRLEad--ghSFVYATDVEvrv-------qelAPEVGRLFEGADVLCLDAQYTPDEYegrkgvaKKGWGH 216 Myxococcus xanthus
EFI33785  149 sHPNLGQGFRISss--grTFVFLTDNElgych---rggasFEEYVRFARDADLLVHDSEFTPEEYr-----qKTGWGH 216 Desulfonatronospira ...
BAH38224  162 nHPGEAAIIRIDdan-gpVMAYAPDNElayansdaahlewLASLYDFLRDVPLLVHDATYTDDELv-----tHVGWGH 233 Gemmatimonas auranti...
EIM65205  149 sHSQDSIGYRFTen--gkTFVFLTDNElgyth---sqgrsVKEYIAFSKDADLLFHDTEYTDDEYl-----nRSGWGH 216 Desulfobacter postga...
EMS77821  149 sHSAGTLGYRFKen--gsTFVFLTDNElgfdh---pqsrgVDAYRQFSMNADVLIHDAEYTQDEYr-----rRKGWGH 216 Desulfotignum phosph...
EGJ51084  146 sHPSPGQGYAIEde--sgRLVFLTDNEldg-------epaLDRYAAFAQNASLLVHDAEYTGSEYa-----lRKGWGH 209 Desulfovibrio africa...
AHG90471  159 hHPDGAVGWRLDdvdgtrLLAFLPDNEideah---grhglRTRWVEMLRGVRLLLHDATYLPADAp-----rHRGWGH 228 Gemmatimonadetes bac...
KMQ50803  147 nHPNGGVGYRFEes--gkSFVFITDNElgfnh---pcgegFSSYVDFCRGADLLFHDAEFNEKEYe-----rFKGWGH 214 haloalkaliphilic bac...
ERP31280  153 hTNGGALGYAIEeg--dtKFVLLTDNElfyah---pqghpYESYVNFARNADLLLHDAQFTQEEYp-----rHLGWGH 220 candidate division T...
CCK81490  149 sHNGGGLGYKFIed--kkTFVFLTDNElgfdh---pegkgFDAYLEFSRNTDLLFHDAEYTENEYs-----lKKGWGH 216 Desulfobacula toluol...

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