Conserved Protein Domain Family
cupin_DRT102
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cd06989: cupin_DRT102 
Arabidopsis thaliana DRT102 and related proteins, cupin domain
This family includes bacterial and eukaryotic proteins homologous to DNA-damage-repair/toleration protein DRT102 found in Arabidopsis thaliana. DRT102 may be involved in DNA repair from UV damage. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.
Links
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Statistics
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PSSM-Id: 380394
Aligned: 91 rows
Threshold Bit Score: 71.023
Created: 23-May-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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metal binding
Feature 1: metal binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:H H [HE] HClick to see conserved feature residue pattern help
Evidence:
  • Comment:The four-coordinate metallocenter usually includes three histidines and one glutamate.
  • Citation:PMID 8612079
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                          # #   #                                       
Q05212       203 MPGGSMKIVRET----PTSAIVRFKAg--SVEPAHHHtfGHDLVVIKgKKSVWNLs----KKERADLvDGDYLFTPagDV 272 thale cress
NP_870592    115 GIEPEIAFLWGQpa-aDQVSGTLVKLpagFTGKFMTAasTFRAVVIRgQLHLHLEg---kDKIAALV-PGSYFGSEgeAT 189 Rhodopirellula ...
EDY80755      49 DLAPKAGTLWGDrn-sDQPTGFLLKPsdgFESPPHIHnvSYRGVVIGgRIHNDDPd----AAEMWMP-AGSFWTQPkgEV 122 Verrucomicrobia...
WP_012802019  27 PDGTRSATLVGTrq-pGVTFTYAFFIpagVWDQPHSHlsDARLVVARgELRLGYGhrldrDAATQHP-VGSFLHVPggAT 104 Kytococcus sede...
OAD22573      56 DKSPKAGTLWGDra-gSGASGFLVKFtdgFSSPPHIHnvTYRGVVISgLIHNDDPd----AKNMWLP-AGSFWTQPagEA 129 Candidatus Thio...
EKK04270      58 DAAPKAGTLWGDqt-eDGESGFLVKFvdgFSSPPHIHnnTYRGVVIAgGLHNDDPd----AEPMWMP-VGSYWTQPsgEV 131 Rhodopirellula ...
SDW92212      67 DKAPMAGTLWGDrk-gTEATGFLLKPkdgFSSPPHIHnvSYRGIVISgLIHNDDPa----AANMWMP-SGSFWTQPkgHV 140 Lutibacter sp. ...
CCQ55648      75 DQSPKAGTLWGDrt-dSGPSGFLVQFvngFSSPPHIHnvTYRGVVISgLVHNDDPg----AENMWLP-AGSFWTQPagEV 148 Crocosphaera wa...
OYU16370      33 ADGTRFALLEGVrnmpGTAFTYAFFIpagAWDGPHTHsaTARVVVARgTLRLGYGnvldkARVQAFP-TGSVLIVPagAR 111 Alphaproteobact...
OUX86150      46 DASPRAGTLWGDra-aEGASGFLVQFkqgFSSPPHIHnvTYRGIVIEgRIHNDDPg----AADMWLP-AGSFWTQPagEA 119 Hyphomonas sp. ...

Feature 1        #                   
Q05212       273 HRVKYh--eDTEFFITWDGH 290 thale cress
NP_870592    190 HAIATd--eETIVYVRTEGT 207 Rhodopirellula baltica SH 1
EDY80755     123 HITAAegsnSLAYIEIEEGP 142 Verrucomicrobiae bacterium DG1235
WP_012802019 105 HFDGAe--vDTILIGTAVGP 122 Kytococcus sedentarius
OAD22573     130 HITAAegrnNLAYIEIEEGP 149 Candidatus Thiomargarita nelsonii
EKK04270     132 HITAArg-dSVAYVEIQEGP 150 Rhodopirellula baltica SH28
SDW92212     141 HITSAkgvnTIAYIEIEKGP 160 Lutibacter sp. UDC377
CCQ55648     149 HITSAddnnNLAYIEIEEGP 168 Crocosphaera watsonii WH 0005
OYU16370     112 HFDGAs--eDTIIIGTAVGP 129 Alphaproteobacteria bacterium PA4
OUX86150     120 HITSAqgafNMAYIEIDEGP 139 Hyphomonas sp. TMED31

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