Conserved Protein Domain Family
ACT_MalLac-Enz

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cd04887: ACT_MalLac-Enz 
ACT_MalLac-Enz CD includes the N-terminal ACT domain of putative NAD-dependent malic enzyme 1, Bacillus subtilis YqkI and related domains
The ACT_MalLac-Enz CD includes the N-terminal ACT domain of putative NAD-dependent malic enzyme 1, Bacillus subtilis YqkI, a malolactic enzyme (MalLac-Enz) which converts malate to lactate, and other related ACT domains. The yqkJ product is predicted to convert malate directly to lactate, as opposed to related malic enzymes that convert malate to pyruvate. Members of this CD belong to the superfamily of ACT regulatory domains.
Statistics
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PSSM-Id: 153159
View PSSM: cd04887
Aligned: 12 rows
Threshold Bit Score: 96.9729
Threshold Setting Gi: 1708922
Created: 15-Mar-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P54572        6 MIRTLMIEtpsVPGNLGRVATAIGllGGDIGEVETVKvgpnyTMRNITVQVEneeQLQEVIAAVQALGEGirLHTVSD 83  Bacillus subtilis
CAD71504     11 TIRLRYSD---SPGAMGKITTAIGeaDGAIGAVDIVNirggkISRDFTVNARdvdHGKRIVEHLRTVEEVe-VVHTSD 84  Rhodopirellula bal...
NP_953357    13 TLRVMITD---QPGYLGRLTTAIGseGGNIGDIRLISsglthNIREITVYVDndqHLEMILKAVAAVEGVi-VEEVID 86  Geobacter sulfurre...
YP_075148    11 IVRLEIEN---TGSIFSYIATAIGasGGDIVAVDLIQsrrdvVVRDITIAVEnraHGDRIVQALAALPGVk-VVNVSD 84  Symbiobacterium th...
BAB76295     13 TLRLQIPN---RVGMLASITQAIAssGGNLGQIDLIEqtrqvSLRDLTVDAAsteHAETIVQAVKAIPDIk-LVSVYD 86  Nostoc sp. PCC 7120
NP_925095    13 TLRLHLPN---QPGMLAKATAAIGeaGGNIGDIELIEqerayTVRDLIVDATseeHAHAIAERVSAIPELk-LLQVDD 86  Gloeobacter violac...
ZP_00515660  13 ALTIELPN---IAGTLANVTQAIAgaQGSFGQISLIEhnlkiTQREITVEASseeHAEQIVSAVREIPNVk-ILKVSD 86  Crocosphaera watso...
ZP_00765967  10 TLRCQIEN---RPGMLGRLTTLIGevGGDIGAIDIVRaerniLVRDITVRVQdeqHGEQLVAAINTLQNIk-VLQVSD 83  Chloroflexus auran...
YP_445903    36 TVRVVISN---RPGMLAKVTSVIGehGGNIGAIDIVRaekdeLTRDITINTRsddHAESIVQALRDLDGVe-VVNISD 109 Salinibacter ruber...
AAK47422     27 LLRIELAD---RPGSLGSLAVALGsvGADILSLDVVErgngyAIDDLVVELPpgaMPDTLITAAEALNGVr-VDSVRP 100 Mycobacterium tube...
YP_474138    13 ALRLRLPN---QPGALARVTQAIAevGGSLSQIDLIHqsaaeTVREICVDAVsseHAEQIRAAVASLPNVk-VERVVD 86  Synechococcus sp. ...
YP_055827    47 MIRIQLPD---TPGSLGSVATAMGtaNADISAIEIVEkgpdyVIDDFILTLPpttMPDTLVSACGMLDEVh-VLWLSR 120 Propionibacterium ...
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