YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate nucleosides. YhcR appears to be the major Ca2+ activated nuclease of B. subtilis. YhcR may be localized in the cell wall.
Comment:Based on similarity to various OB folds with structures.
Comment:The generic binding surface I contains nucleic acid partners in most OB-fold complexes. In some cases, this surface may also contain the sites for protein-protein interaction.
Jiyao W et al.(2023). "The conserved domain database in 2023.",