1FHF,6ATJ,3HDL,1BGP,1QGJ,1PA2,1SCH


Conserved Protein Domain Family
secretory_peroxidase

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cd00693: secretory_peroxidase 
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Horseradish peroxidase and related secretory plant peroxidases.
Secretory peroxidases belong to class III of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class III peroxidases are found in the extracellular space or in the vacuole in plants where they have been implicated in hydrogen peroxide detoxification, auxin catabolism and lignin biosynthesis, and stress response. Class III peroxidases contain four conserved disulphide bridges and two conserved calcium binding sites.
Statistics
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PSSM-Id: 173827
View PSSM: cd00693
Aligned: 155 rows
Threshold Bit Score: 300.584
Threshold Setting Gi: 115462761
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 29 residues -Click on image for an interactive view with Cn3D
Feature 1:heme binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                        #  ## ##  #                              #  # # 
1FHF_A         1 QLTPTFYRE--TCPNLFPIVFGVIFDASftDPRIGASLMRLHFHDCFVqgCDGSVLLnnt--dtiESEQDALPNinSIRG 76  soybean
CAA17163      23 GLMMNFYKD--TCPQAEDIVREQVKLLYkrHKNTAFSWLRNIFHDCAVesCDASLLLdst--rreLGEKEHDRSf-GLRN 97  thale cress
NP_001054980   9 GLSGDYYRR--SCPQLELVVDMALAPVFavDQTSPAALLRLFFHDCQVqgCDGSILLnsderrniTSELGSDKNf-GIRD 85  Japanese rice
1403138       29 ELEMNYYKE--SCPKAEEIIRQQVETLYykHGNTAVSWLRNLFHDCVVksCDASLLLeta--rgvESEQKSKRSf-GMRN 103 thale cress
BAB97197      32 QLDQNYYVG--TCPNVENLVNQWLVANVftDPTGPAALVRLVFHDCQVngCDGSVLLdtq--pgaVSELESDANf-GIRD 106 liverwort
O81755        67 YLHYDYYRE--SCPTAEKIIAKAIRDIYnvTPSVAPPIIRLLFHDCFIegCDASVLLdad--eahTSEKDASPNl-SLKG 141 thale cress
EAZ05247      28 GLKLNFYSEseRCPRAEEVVREEVRRLYeeHGNTAVSWLRALFHDCMVysCDASLLLhttt-ttgVSEQSSHRSf-GMRN 105 Indian rice
CAN70977      24 GLSYSIYQK--SCPQVEDIVRAALGPIFlsDPSSPPAFLRLLFHDCQVqgCDASILVdpag-gktPLEMASSKNf-GVRK 99  wine grape
NP_566565     37 GLSYSYYEK--TCPKVEEIVRSSLSSMFilDPTSPAALLRLMFHDCQVqgCDASILLepir-dqqFTELDSAKNf-GIRK 112 thale cress
EEF46476      75 SLEYDFYRN--SCPQAEKIIQNVVRELYkvKFSVSPALLRLVFHDCFIagCDASILLdav--dgkQSEKDSNPNe-NLKG 149 castor bean
Feature 1                                                                                ###     
1FHF_A        77 LDVVNDIKTAVENSCPDTVSCADILAIAAEIASVLGg-GPGWPVPLGRRDSlta---nrTLANq------nLPAPFFnLT 146 soybean
CAA17163      98 FRYIEEIKEALERECPGVVSCSDILVLSAREGIEAVg-GPYIPLKTGRRDGl------kSRTDmle---syLPDHNEsIS 167 thale cress
NP_001054980  86 VSTIGLVKAAVERACPGQVSCADIVVLAARSAVAHAggPRIRGVPLGRRDAt------aASAErad---amLPDSFLgID 156 Japanese rice
1403138      104 FKYVKIIKDALEKECPSTVSCADIVALSARDGIVMLkgPKIEMIKTGRRDSr------gSYLGdve---tlIPNHNDsLS 174 thale cress
BAB97197     107 LRFIDSIKAAVELACPGVVSCTDILALAARDCVRLTg-GPSIRIPLGRKDG--------RSASnlaa-drqLPPSDIsVP 176 liverwort
O81755       142 FDVIDAVKSELENVCPGVVSCADLLVLAAREAVLVAg-GPFYPLETGRKDS--------AAAYrdfa-eheLPAPDAtLS 211 thale cress
EAZ05247     106 FKYITAIKAAVERECPATVSCADILALAARDGVAMLg-GPSVAMRTGRRDS--------RESYygvv-eqyIPNHNDsVS 175 Indian rice
CAN70977     100 RESISLIKSVVEAQCPGTVSCADILVMAARDAVAFSg-GPWIKVPFGRRDS--------SRATsykladalLPPANXdVN 170 wine grape
NP_566565    113 RDLVGSIKTSLELECPKQVSCSDVIILAARDAVALTg-GPLISVPLGRKDSlstpskhvADSE--------LPPSTAdVD 183 thale cress
EEF46476     150 YDIIDKIKSQIEEVCPGIVSCADIVVLAAREGVLQAg-GPFYPLFTGRRDSte----pfSNLAtn-----eLPSPNAdLS 219 castor bean
Feature 1         #   #         #  ## ## #####  #                                                
1FHF_A       147 QLKASFAVQGlNTLDLVTLSGGHTFGRARCSTFinrlynfsntgnpdptlntTYLEVLRARCPqna------------tg 214 soybean
CAA17163     168 VVLEKFKSIGiDTPGLVALLGSHSVGRTHCVKLvhrlype-----vdpslnpDHVPHMLHKCPdsipd---------pka 233 thale cress
NP_001054980 157 GALAMFQSKGmTVEETVAILGGHTLGGGHCATVdtarrg-------rgrsdaAFEAALRLACPaaapr--------avaa 221 Japanese rice
1403138      175 SVISTFNSIGiDVEATVALLGAHSVGRVHCVNLvhrlypt-----idptldpSYALYLKKRCPsptpd---------pna 240 thale cress
BAB97197     177 AFLSEFAQMGmTADEAVAIIGAHTIGVGHCVNVvnrlfpq-----qdpalspLMAGQLLTQCPtpnaa--------flnn 243 liverwort
O81755       212 VILQRFSFRGfNERETVSLFGAHSIGITHCTFFknrlynfsatgkpdpelnpGFLQELKTKCPfsvstsspsappdiglp 291 thale cress
EAZ05247     176 TVLSRFAAIGvDTEGAVALLGAHSVGRVHCFNLvgrlypq-----vdgsmeaAYGEYLRGRCPtaaate-------dtre 243 Indian rice
CAN70977     171 GXLQIFTQKGmTIKEAVAIIGAHTIGITHCLNIrdrlqrpeg-ggrargmepGFEAFLRLSCPegsl----------isn 239 wine grape
NP_566565    184 TTLSLFANKGmTIEESVAIMGAHTIGVTHCNNVlsrfdnan---atsenmdpRFQTFLRVACPefspts-------qaae 253 thale cress
EEF46476     220 ETLASFSSRGfDERETVSILGAHSIGMIHCKFFlnrlydfggtygpdpsldpQFLNFLRSKCNtsgas---------evp 290 castor bean
Feature 1             #                                                                          
1FHF_A       215 dNLTNLDl------------------------------------STPDQFDN------------------------RYYS 234 soybean
CAA17163     234 vQYVRNDr------------------------------------GTPMVLDN------------------------NYYR 253 thale cress
NP_001054980 222 aVPVLSD-------------------------------------ATPSWFDN------------------------LYYW 240 Japanese rice
1403138      241 vLYSRNDr------------------------------------ETPMVVDN------------------------MYYK 260 thale cress
BAB97197     244 nTILSND-------------------------------------FTNFVFDN------------------------QYYR 262 liverwort
O81755       292 pSLPASDsens------------------------------ygmSSGNRNDEvidlsynne-------ggdenfgtRYFR 334 thale cress
EAZ05247     244 vVYARNDr------------------------------------VTPMLIDN------------------------MYYR 263 Indian rice
CAN70977     240 sTFVVND-------------------------------------PSAFTFDN------------------------HYYS 258 wine grape
NP_566565    254 aTFVPND-------------------------------------QTSVIFDT------------------------AYYD 272 thale cress
EEF46476     291 aASPPFDilvssstetspphsvmssaappslsfrgslsspplctAPSVSFENsllsspedlginmayegpgvdfgtLYYR 370 castor bean
Feature 1                # #                                 #                         
1FHF_A       235 NLLQlNGLLQSDQELFSTpgaDTIPIVNSFSSNqNTFFSNFRVSMIKMGNIgvlt--gdeGEIRLQCNFV 302 soybean
CAA17163     254 NILDnKGLLLVDHQLAHDk--RTRPIVKKMAKDqAYFFKEFTRAIQILSENnplt--gskGEIRKQCNLA 319 thale cress
NP_001054980 241 NAASgRGIFAVDAEEAADa--RTAGHVRRFAADgRRFFRAFSSAFVKLAMSgvlt--gdeGEIRRRCDVV 306 Japanese rice
1403138      261 NIMAhKGLLVIDDELATDp--RTAPFVAKMAADnNYFHEQFSRGVRLLSETnplt--gdqGEIRKDCRYV 326 thale cress
BAB97197     263 DVMNgNGLFKIDSLIGQNp--TTAGIVARFAANqNDFFGVFSRAFVKMTSFrvlt--gaqGEVRRNCHRL 328 liverwort
O81755       335 RLMQnKGLMSSDQQLMGSe--VTEMWVRAYASDpLLFRREFAMSMMKLSSYnvlt--gplGQVRTSCSKA 400 thale cress
EAZ05247     264 NLLAgRGLLLVDQQLASDa--RTAPYVRRMAADnDYFHQRFAAALLTMSENaplt--gaqGEVRKDCSAS 329 Indian rice
CAN70977     259 NAMHgRGILRVDAEVSSDs--RTAPIVSSFAADqRRDIKEGWVGIPDYGGGsmvgsivypQKGSLGCVPF 326 wine grape
NP_566565    273 DAIAgRGNLRIDSEIGADp--RTRPFVEAFAADqDRFFNAFSSAFVKLSSYkvlt--gneGVIRSVCDKV 338 thale cress
EEF46476     371 SLLHgRGILYSDQQLMSGe--ETGIWVRAYASDvSLFRRDFAQAMMKLSNLnvlt--gsaGQVRRNCSKV 436 castor bean

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