1RF4


Conserved Protein Domain Family
aroA

?
TIGR01356: aroA 
Click on image for an interactive view with Cn3D
3-phosphoshikimate 1-carboxyvinyltransferase
This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Statistics
?
PSSM-Id: 273574
Aligned: 19 rows
Threshold Bit Score: 454.426
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1RF4_A         12 GIIRVPGDKSISHRSIIFGSLAEGETKVYDILRGEDVLSTMQVFRDLG-VEIE-DK-DGVITVQGVGMaglKAPQ----- 83   Streptococcus...
Q9RND7         17 GEVALPGSKSISNRVLLLAALAEGSTEITGLLDSDDTRVMLAALRQLG-VSVGeVAdG-CVTIEGVA----RFPTe---- 86   Bordetella br...
Q9YEK9         19 GRVEAPPSKSYTHRMLFLALLARGRSVVRRPLVSNDTLATLNAVALLG-GKPR-LG-RGVAEVEG--Ge--VRGG----- 86   Aeropyrum per...
Q9PK28         17 GEFSIPPSKSHSLRAILFASLSKGTSIINNSLSSPDTDTMLSACKKFG-ARIT-RV-GETLHIQGNPp---PYSQys--- 87   Chlamydia mur...
Q9RVD3         21 GELRAQPSKNYTTRYLLAAALAEGETRVVGVATSEDAEAMLRCLRDWG-AGVE-LV-GDDAVIRGFG----ARPQa---- 89   Deinococcus r...
Q9HQC1         21 GRARAPPSKSYTHRALLAAGYADGETVVRDPLVSADTRATARAVELLG-GAAA-RE-NGDWVVTG-FGsrpAIPD----- 91   Halobacterium...
Q9K9D5         32 GSITLPGSKSLTNRALIISALANSDSMLTGMLKSDDTYWCIQALKRLG-VQINvQ--GETTSIRGIGG---QWKSs---- 101  Bacillus halo...
Q9P7R0        407 VVVTPPGSKSISNRALVLAAMGNGTCRLTNMLHSDDTQFMMSALESLGaATFSwEDgGETLVVKGNGG---KLAVp---- 479  Schizosacchar...
WP_010867580   19 GKVKAPPSKSYTHRAYFLSLLADSPSKVMNPLISEDTIASLDAISKFG-AQVN--G-NKIIPPQE------LTPG----- 83   Pyrococcus ab...
P05466         91 GLIKLPGSKSLSNRILLLAALSEGTTVVDNLLNSDDINYMLDALKRLG-LNVEtDSeNNRAVVEGCGG---IFPAsidsk 166  thale cress
1RF4_A         84 --NALNMGNSGTSIRLISGVLAGAD-----FEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERdLPPLRLKGT--KN 154  Streptococcus...
Q9RND7         87 -qAELFLGNAGTAFRPLTAALALMG-----GDYRLSGVPRMHERPIGDLVDALRQFGAGIEYLGQAgYPPLRIGGGs-IR 159  Bordetella br...
Q9YEK9         87 --AVVYAAGSGTTIRIAMGVAA-HSa----EATLLYGDESLNRRPVHPLSEALRSMGARVCD--TGgNPPVKVSGp--LR 155  Aeropyrum per...
Q9PK28         88 -sHHFHMGNSGIALRFLTALSSLSP-----SPILITGAHTLKRRPIEPLLSSLEQLGSEIRQKKSs-SIPFVIRGP--IS 158  Chlamydia mur...
Q9RVD3         90 -gVTLNPGNAGAVARFLMGVAALTSg----TTFVTDYPDSLGKRPQGDLLEALERLGAWVSSNDg--RLPISVSGP--VR 160  Deinococcus r...
Q9HQC1         92 --AVIDCANSGTTMRLVTAAAA-LAd----GTTVLTGDESLRARPHGPLLDALSGLGGTARSTRGNgQAPLVVDGP--VS 162  Halobacterium...
Q9K9D5        102 ---SLYIGAAGTLARFLLGALAISRs----GNWEIEASQSMSKRPIEPLVGVLRELGATIHYLRREgFYPLSIHGNg-LA 173  Bacillus halo...
Q9P7R0        480 -kEELYLGNAGTAARFLTGIAALVSskdgaK-VVLTGNHRMKVRPIGPLVDALRANGCEINYLEKQgSLPLDLSSKngLK 557  Schizosacchar...
WP_010867580   84 --K-IDARESGTTARISLAVASLAR-----GTSVITGKGRLVERPFKPLVDALRSLKVKIS----GeKLPIAVEGG--NP 149  Pyrococcus ab...
P05466        167 sdIELYLGNAGTAMRPLTAAVTAAGg---nASYVLDGVPRMRERPIGDLVVGLKQLGADVECTLGTnCPPVRVNANggLP 243  thale cress
1RF4_A        155 LrP-IHYELPIASAQVKSALMFAA-------LQAKGESVIIeKEYTRNHTEDMLQQFGGHls----vDG--KKITVQGPQ 220  Streptococcus...
Q9RND7        160 VdG-PVRVEGSVSSQFLTALLMAApvlarrsGQDITIEVVG-ELISKPYIEITLNLMARFgvs-vrrDGw-RAFTIARDA 235  Bordetella br...
Q9YEK9        156 R-A-SVEVDAAISSQFATSLLIAGs-----rL--GEFELSAaRLSSRGYVDITLESLSMFgvrvereGY--RLFRLR--G 222  Aeropyrum per...
Q9PK28        159 S-G-HVTISGQ-DSQYASALAITAav----aPHPLSFSIEN--LKERPWFDLTLDWLHSLnisfsreQD---SLFFPGAQ 226  Chlamydia mur...
Q9RVD3        161 G-G-TVEVSAERSSQYASALMFLGpl----lPDGLELRLTG-DIKSHAPLRQTLDTLSDFgvratasDDl-RRISIPGGQ 232  Deinococcus r...
Q9HQC1        163 G-G-SVALPGDVSSQFVTALLMAGav---teT--GIETDLTtELKSAPYVDITLDVLDAFgvgasetAA---GYRVRGGQ 232  Halobacterium...
Q9K9D5        174 G-G-TVRLSGQMSSQYISGLLIAApy----aDTPVTITVQG-SIVQHAYVFLTLHLMKSFgaqveydQQl-QTIVVHPTP 245  Bacillus halo...
Q9P7R0        558 G-G-IIELAATVSSQYVSSILMCApy----aSQPVTLKLVGgKPISQLYIDMTIAMMASFgvnvtksTTeeNTYNIPCG- 630  Schizosacchar...
WP_010867580  150 V-GeYVKVDCSLSSQFGTAMLILAsk--------iGLTVEMlNPVSRPYIEVTLKVMESFgiefernGF---KVKVHPG- 216  Pyrococcus ab...
P05466        244 G-G-KVKLSGSISSQYLTALLMSApl----aLGDVEIEIVD-KLISVPYVEMTLKLMERFgvsvehsDSw-DRFFVKGGQ 315  thale cress
1RF4_A        221 KLTGQk--VVVPGDIS-SAAFWLVAGLIAPNs--RLVLQNVGINETRTGi--ID-VIRAMGGKLEITEIDpvaksatLIV 292  Streptococcus...
Q9RND7        236 AYRGPg-rMAIEGDAS-TASYFLALGAIGGG---PVRVTGVGEDSIQGDvafAA-TLAAMGADVRYGPGW-------IET 302  Bordetella br...
Q9YEK9        223 TPKPVd--AAVPGDYS-SASFMLAAGAIAG----RVEVEGLRPVDPQPDrriVE-LLRSMGARVRVEGGv-------VAV 287  Aeropyrum per...
Q9PK28        227 SIKSFs--YSVPGDYS-SAAFLAALGLLSSSs-nPTVLYNLPSKDPQGDkqlFS-LLKSLGADIVIEKDH-------IEI 294  Chlamydia mur...
Q9RVD3        233 KYRPGr--VLVPGDYPgSAAILTAAALLPG----EVRLSNLREHDLQGEkeaVN-VLREMGADIVREGDT-------LTV 298  Deinococcus r...
Q9HQC1        233 AYAPSgaeYAVPGDFS-SASYLLAAGALAAAdgaAVVVEGMHP-SAQGDaaiVD-VLERMGADIDWDTEs------gVIT 303  Halobacterium...
Q9K9D5        246 -YTCQd--IDLEADAS-TACYFLALAALTKG---RIRLNNLTASTTQPDlhmLT-VFEKMGCTVTRGSSF-------IEL 310  Bacillus halo...
Q9P7R0        631 KYQNPp-hYEIESDAS-SATYPLAIAAITGT---KCTVPNIGSASLQGDarfACdVLRPMGCTVEQTATS-------TTV 698  Schizosacchar...
WP_010867580  217 -IRGSk--FHVPGDYS-SASFFLAAGALYG----KVKVSNLVKDDPQADariID-ILEEFGADVKVGRKY-------VVV 280  Pyrococcus ab...
P05466        316 KYKSPg-nAYVEGDAS-SASYFLAGAAITGE---TVTVEGCGTTSLQGDvkfAE-VLEKMGCKVSWTENS-------VTV 382  thale cress
1RF4_A        293 E-----SSDLKGTE----IcgaLIPRLIDELPIIALLATQA------QGVTVIKDAEELKVKETDRIQVVADALNSMGAD 357  Streptococcus...
Q9RND7        303 Rgv-rvAEGGR-LKaf-dA---DFNLIPDAAMTAATLALYA------DGPCRLRNIGSWRVKETDRIHAMHTELEKLGAG 370  Bordetella br...
Q9YEK9        288 Es----TGPLEPVD----V---DLDGSPDLAPVAAVLAAYA------RGVSRLRGLERLKYKESDRLSAIAWNLARLGVE 350  Aeropyrum per...
Q9PK28        295 R-----PSSFSGGV----I---DMDPFIDALPILAVLCCFA------KNPSHLYNALGARDKESNRIEAIAHELRKMGGS 356  Chlamydia mur...
Q9RVD3        299 Rg----GRPLHAVT----R---DGDSFTDAVQALTAAAAFA------EGDTTWENVATLRLKECDRISDTRAELERLGLR 361  Deinococcus r...
Q9HQC1        304 Vq----RSELSGVE----V---GVADTPDLLPTIAVLGAAA------DGTTRITDAEHVRYKETDRVAAMAESLSKLGAS 366  Halobacterium...
Q9K9D5        311 Egv-sqLKGG--FQ----I---SMNEMSDQALTLAAIAPFA------DGPITITDVEHIRYHESDRIAVICEALTRLGIQ 374  Bacillus halo...
Q9P7R0        699 Qg---pPKGT--LKplesI---DMETMTDAFLTASVVAAVAcnvsegDPVTRITGIANQRVKECNRIAAMVHELAKFGVR 770  Schizosacchar...
WP_010867580  281 Er----N-EMKPIN----V---DCSNFPDLFPILAVLASYA------EGKSVITG-RQLRLKESDRVKAVAVNLRKAGIK 341  Pyrococcus ab...
P05466        383 TgpprdAFGMRHLRai-dV---NMNKMPDVAMTLAVVALFA------DGPTTIRDVASWRVKETERMIAICTELRKLGAT 452  thale cress
1RF4_A        358 ITPTADGMIIKGK---SALHG--ARVNTFGDHRIGMMTAIAAlLVADg-EVELDRAEAINTSYPSFFDDLESLIHG 427  Streptococcus pne...
Q9RND7        371 VQSGADWLEVAPPa-pGGWRD--AHIGTWDDHRMAMCFSLAA-FGPA--AVRILDPGCVSKTFPDYFDVYAGLLAA 440  Bordetella bronch...
Q9YEK9        351 ARVRGGILEIRGGg----VEG--GVARSWGDHRIAMAMAVAG-LGARr-PVAVEGFSRVPDSYPGFLEDLARLGAR 418  Aeropyrum pernix K1
Q9PK28        357 VHPTQDGLYIEPS----RLHG--AVVHSHNDHRIAMALAVAG-VHASsgQTLLCNTQCVNKSFPHFVIAAQTLHAN 425  Chlamydia muridar...
Q9RVD3        362 ARETADSLSVTGS---AHLAGg-ITADGHGDHRMIMLLTLLG-LRADa-PLRITGAHHIRKSYPQFFAHLEALGAR 431  Deinococcus radio...
Q9HQC1        367 VEERPDELVVRGGd--TELSG--ASVDGRGDHRLVMALAVAG-LVADg-ETTIAGSEHVDVSFPDFFEVLAGLGAD 436  Halobacterium sp....
Q9K9D5        375 VDEFEDGLTVYPGtpkPTLH----PLSTYDDHRVAMSLSLIG-TKVK--GLRLNDPGCVAKTCPSYFQLLEQLGIQ 443  Bacillus halodura...
Q9P7R0        771 TGELEDGIYIFGKn-yKELKKpeEGIYTYDDHRIAMSFSVLS-LICPs-RTLIIDKACVEKTWPYWWDVLHQSFGV 843  Schizosaccharomyc...
WP_010867580  342 VKELPNGLEIVGG---K-PRG--FTVESFNDHRIVMAMAILG-LGAEg-KTIIKDPHVVSKSYPSFFLDLRRVLNE 409  Pyrococcus abyssi
P05466        453 VEEGSDYCVITPP---KKVKT--AEIDTYDDHRMAMAFSLAA-CADV--PITINDPGCTRKTFPDYFQVLERITKH 520  thale cress
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap