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Report for CCDS4188.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
4188.2 Public Homo sapiens 5 CXCL14 24 110 108 CCDS HistoryNCBI Gene:9547Re-query CCDS DB by CCDS ID:4188.2See the combined annotation on chromosome 5 in Sequence Viewer

Public Note for CCDS 4188.1
This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. An alternative downstream start codon, which is more widely conserved and has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 12 aa shorter at the N-terminus. Both the longer and shorter proteins have N-terminal signal peptides, as predicted by SignalP 3.0. There is no experimental evidence showing which start codon is preferentially used in vivo.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
CDS uses downstream AUG

Sequence IDs included in CCDS 4188.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000512158.6 ENSP00000423783.1 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000512158.6Link to Ensembl Protein Viewer:ENSP00000423783.1Re-query CCDS DB by Nucleotide ID:ENST00000512158Re-query CCDS DB by Protein ID:ENSP00000423783
Original member Current member NCBI NM_004887.5 NP_004878.3 MANE Select Accepted alive Link to Nucleotide Sequence:NM_004887.5Link to Protein Sequence:NP_004878.3Re-query CCDS DB by Nucleotide ID:NM_004887Re-query CCDS DB by Protein ID:NP_004878Link to BLAST:NP_004878.3

Chromosomal Locations for CCDS 4188.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 5 (NC_000005.10)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5See the combined annotation on chromosome 5 in Sequence Viewer

Chromosome Start Stop Links
5 135571853 135571868 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 135574572 135574685 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 135578434 135578539 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5
5 135578715 135578778 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 5Link to Ensembl Genome Browser on chromosome 5

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (300 nt):
ATGAGGCTCCTGGCGGCCGCGCTGCTCCTGCTGCTGCTGGCGCTGTACACCGCGCGTGTGGACGGGTCCA
AATGCAAGTGCTCCCGGAAGGGACCCAAGATCCGCTACAGCGACGTGAAGAAGCTGGAAATGAAGCCAAA
GTACCCGCACTGCGAGGAGAAGATGGTTATCATCACCACCAAGAGCGTGTCCAGGTACCGAGGTCAGGAG
CACTGCCTGCACCCCAAGCTGCAGAGCACCAAGCGCTTCATCAAGTGGTACAACGCCTGGAACGAGAAGC
GCAGGGTCTACGAAGAATAG

Translation (99 aa):
MRLLAAALLLLLLALYTARVDGSKCKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVIITTKSVSRYRGQE
HCLHPKLQSTKRFIKWYNAWNEKRRVYEE


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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