nudt17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nudt17provided by ZNC
Official Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 17provided by ZNC
Primary source: ZFIN:ZDB-GENE-050913-50
See related: Ensembl:ENSDARG00000008014 AllianceGenome:ZFIN:ZDB-GENE-050913-50
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:114128
Summary: Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NAD catabolic process; NADH metabolic process; and NADP catabolic process. Predicted to be active in peroxisome. Orthologous to human NUDT17 (nudix hydrolase 17). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (43000828..43011494, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (43097070..43107736, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NADH pyrophosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NAD catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in NADH metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in NADP catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nucleoside diphosphate-linked moiety X motif 17

Names: nudix motif 17

NP_001025274.1

EC 3.6.1.-

XP_005158331.1

EC 3.6.1.-

XP_021322369.1

EC 3.6.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030103.1 → NP_001025274.1 nucleoside diphosphate-linked moiety X motif 17

See identical proteins and their annotated locations for NP_001025274.1

Status: PROVISIONAL

Source sequence(s)

BC097186

UniProtKB/Swiss-Prot

Q4V8V2

Related

ENSDARP00000006375.6, ENSDART00000017966.8

Conserved Domains (1) summary

cd04694
Location:92 → 234

Nudix_Hydrolase_35; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

43000828..43011494 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005158274.5 → XP_005158331.1 nucleoside diphosphate-linked moiety X motif 17 isoform X1

UniProtKB/TrEMBL

A0A8M2B4L8, F1QMV9

Conserved Domains (1) summary

cd04694
Location:92 → 234

Nudix_Hydrolase_35; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
XM_021466694.2 → XP_021322369.1 nucleoside diphosphate-linked moiety X motif 17 isoform X2

UniProtKB/TrEMBL

A0A8M9PD41

Related

ENSDARP00000121423.1, ENSDART00000142003.3

Conserved Domains (1) summary

cd04694
Location:92 → 234

Nudix_Hydrolase_35; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...