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NUDT17 nudix hydrolase 17 [ Homo sapiens (human) ]

Gene ID: 200035, updated on 12-Oct-2019

Summary

Official Symbol
NUDT17provided by HGNC
Official Full Name
nudix hydrolase 17provided by HGNC
Primary source
HGNC:HGNC:26618
See related
Ensembl:ENSG00000186364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in skin (RPKM 3.7), endometrium (RPKM 3.3) and 25 other tissues See more
Orthologs

Genomic context

See NUDT17 in Genome Data Viewer
Location:
1q21.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (145844985..145848954)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145586491..145589435, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CD160 molecule Neighboring gene ring finger protein 115 Neighboring gene RNA polymerase III subunit C Neighboring gene microRNA 6736 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene ankyrin repeat domain 35

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ34433

Gene Ontology Provided by GOA

Function Evidence Code Pubs
NADH pyrophosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
NAD catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NADH metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
NADP catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
nucleoside diphosphate-linked moiety X motif 17
Names
nudix (nucleoside diphosphate linked moiety X)-type motif 17
nudix motif 17
NP_001012776.1
XP_011507562.1
XP_011507564.1
XP_016856049.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012758.3NP_001012776.1  nucleoside diphosphate-linked moiety X motif 17

    See identical proteins and their annotated locations for NP_001012776.1

    Status: VALIDATED

    Source sequence(s)
    AC239808
    Consensus CDS
    CCDS72865.1
    UniProtKB/Swiss-Prot
    P0C025
    Related
    ENSP00000334437.5, ENST00000334513.6
    Conserved Domains (1) summary
    cd04694
    Location:92234
    Nudix_Hydrolase_35; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    145844985..145848954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011509260.2XP_011507562.1  nucleoside diphosphate-linked moiety X motif 17 isoform X1

    Conserved Domains (1) summary
    cl00447
    Location:55164
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
  2. XM_011509262.1XP_011507564.1  nucleoside diphosphate-linked moiety X motif 17 isoform X2

    Conserved Domains (1) summary
    cl00447
    Location:92198
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
  3. XM_017000560.1XP_016856049.1  nucleoside diphosphate-linked moiety X motif 17 isoform X3

RNA

  1. XR_001737030.1 RNA Sequence

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