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esr1 estrogen receptor 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 394461, updated on 25-Apr-2024

Summary

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Official Symbol
esr1provided by Xenbase
Official Full Name
estrogen receptor 1provided by Xenbase
Primary source
Xenbase:XB-GENE-482193
See related
Ensembl:ENSXETG00000012364
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
XER; era; esr; esra; nr3a1; xesr1; ERbeta; esr1-a; esr1-b; xesr-1; ERalpha; xlERalpha1; xlERalpha2
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See esr1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (48771409..48850097, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (37531206..37610115, complement)

Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene MYC target 1 Neighboring gene spectrin repeat containing, nuclear envelope 1 Neighboring gene coiled-coil domain containing 170 Neighboring gene zinc finger and BTB domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning of two isoforms of Xenopus (Silurana) tropicalis estrogen receptor mRNA and their expression during development. Takase M, et al. Biochim Biophys Acta, 2007 Mar. PMID 17346814
  2. Estrogen receptor expression in laryngeal muscle in relation to estrogen-dependent increases in synapse strength. Wu KH, et al. Neuroendocrinology, 2003 Aug. PMID 12915759
  3. Estrogen receptors in Xenopus: duplicate genes, splice variants, and tissue-specific expression. Wu KH, et al. Gen Comp Endocrinol, 2003 Aug. PMID 12899845
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables steroid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within steroid hormone mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in zymogen activation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
estrogen receptor
Names
estrogen receptor alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203535.1 → NP_988866.1  estrogen receptor precursor

    See identical proteins and their annotated locations for NP_988866.1

    Status: PROVISIONAL

    Source sequence(s)
    AY310902
    UniProtKB/TrEMBL
    F7BMW5, Q25C14, Q6W5G9
    Related
    ENSXETP00000027035.3, ENSXETT00000027035.5
    Conserved Domains (4) summary
    cd06949
    Location:259 → 496
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:132 → 213
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:40 → 133
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:509 → 543
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    48771409..48850097 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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