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qtrt1 queuine tRNA-ribosyltransferase 1 [ Danio rerio (zebrafish) ]

Gene ID: 393985, updated on 12-Sep-2024

Summary

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Official Symbol
qtrt1provided by ZNC
Official Full Name
queuine tRNA-ribosyltransferase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1625
See related
Ensembl:ENSDARG00000043105 AllianceGenome:ZFIN:ZDB-GENE-040426-1625
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:66378
Summary
Predicted to enable protein heterodimerization activity; protein homodimerization activity; and queuine tRNA-ribosyltransferase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to act upstream of or within tRNA modification. Predicted to be located in mitochondrial outer membrane. Orthologous to human QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (47114326..47128096, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (50303686..50317456, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene potassium sodium-activated channel subfamily T member 2b Neighboring gene uncharacterized LOC101883904 Neighboring gene dynamin 2a Neighboring gene microRNA 199-2a Neighboring gene transmembrane p24 trafficking protein 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Biswas G, et al. Mar Genomics, 2015 Aug. PMID 25792259
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC66378

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pentosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tRNA-guanosine(34) queuine transglycosylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA-guanosine(34) queuine transglycosylase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA-guanosine(34) queuine transglycosylase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA modification IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA-guanine transglycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tRNA-guanine transglycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
queuine tRNA-ribosyltransferase catalytic subunit 1
Names
guanine insertion enzyme
tRNA-guanine transglycosylase
NP_957304.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201010.1 → NP_957304.1  queuine tRNA-ribosyltransferase catalytic subunit 1

    See identical proteins and their annotated locations for NP_957304.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054695
    UniProtKB/Swiss-Prot
    Q7SYK1
    Related
    ENSDARP00000063286.3, ENSDART00000063287.4
    Conserved Domains (2) summary
    COG0343
    Location:24 → 376
    Tgt; Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]
    cl19224
    Location:24 → 376
    TGT; Queuine tRNA-ribosyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    47114326..47128096 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7SYK1.1 GenPept UniProtKB/Swiss-Prot:Q7SYK1

Gene LinkOut

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