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    ITSN2 intersectin 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 475683, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ITSN2provided by VGNC
    Official Full Name
    intersectin 2provided by VGNC
    Primary source
    VGNC:VGNC:42162
    See related
    Ensembl:ENSCAFG00845023729
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 17
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (18901627..19030962, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (18525190..18654045, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (18687565..18789791, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (18638301..18766826, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (18647161..18776232, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 228, member B Neighboring gene profilin family member 4 Neighboring gene uncharacterized LOC111090423 Neighboring gene uncharacterized LOC111090532

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    intersectin-2; LOW QUALITY PROTEIN: intersectin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      18901627..19030962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038690855.1 → XP_038546783.1  intersectin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3PP11
      Conserved Domains (11) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1575 → 1709
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    2. XM_038690858.1 → XP_038546786.1  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8I3PP11
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    3. XM_038690856.1 → XP_038546784.1  intersectin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PKP1
      Conserved Domains (11) summary
      cd08375
      Location:1548 → 1682
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:754 → 810
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:895 → 946
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:978 → 1029
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1050 → 1108
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1123 → 1176
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:388 → 762
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1203 → 1386
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1405 → 1548
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    4. XM_038690857.1 → XP_038546785.1  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8I3PP11
      Related
      ENSCAFP00845033183.1, ENSCAFT00845042328.1
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    5. XM_038690859.1 → XP_038546787.1  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8I3PP11
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    6. XM_038690860.1 → XP_038546788.1  intersectin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8I3PKP1
      Related
      ENSCAFP00845033373.1, ENSCAFT00845042567.1
      Conserved Domains (11) summary
      cd08375
      Location:1514 → 1648
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:720 → 776
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:861 → 912
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:944 → 995
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1016 → 1074
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1089 → 1142
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:354 → 728
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1169 → 1352
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1371 → 1514
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    7. XM_038690861.1 → XP_038546789.1  intersectin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NNK7
      Conserved Domains (10) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      18638301..18766826 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038498356.1 → XP_038354284.1  intersectin-2 isoform X1

      Conserved Domains (11) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1575 → 1709
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    2. XM_038498359.1 → XP_038354287.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    3. XM_038498357.1 → XP_038354285.1  intersectin-2 isoform X2

      Conserved Domains (11) summary
      cd08375
      Location:1548 → 1682
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:754 → 810
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:895 → 946
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:978 → 1029
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1050 → 1108
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1123 → 1176
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:388 → 762
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1203 → 1386
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1405 → 1548
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    4. XM_038498358.1 → XP_038354286.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    5. XM_038498360.1 → XP_038354288.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    6. XM_038498361.1 → XP_038354289.1  intersectin-2 isoform X4

      Conserved Domains (11) summary
      cd08375
      Location:1514 → 1648
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:720 → 776
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:861 → 912
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:944 → 995
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1016 → 1074
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1089 → 1142
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:354 → 728
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1169 → 1352
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1371 → 1514
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    7. XM_038498362.1 → XP_038354290.1  intersectin-2 isoform X5

      Conserved Domains (10) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      18647161..18776232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038624946.1 → XP_038480874.1  intersectin-2 isoform X1

      Conserved Domains (11) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1575 → 1709
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    2. XM_038624949.1 → XP_038480877.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    3. XM_038624947.1 → XP_038480875.1  intersectin-2 isoform X2

      Conserved Domains (11) summary
      cd08375
      Location:1548 → 1682
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:754 → 810
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:895 → 946
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:978 → 1029
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1050 → 1108
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1123 → 1176
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:388 → 762
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1203 → 1386
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1405 → 1548
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    4. XM_038624948.1 → XP_038480876.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    5. XM_038624950.1 → XP_038480878.1  intersectin-2 isoform X3

      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    6. XM_038624951.1 → XP_038480879.1  intersectin-2 isoform X4

      Conserved Domains (11) summary
      cd08375
      Location:1514 → 1648
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:720 → 776
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:861 → 912
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:944 → 995
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1016 → 1074
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1089 → 1142
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:354 → 728
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1169 → 1352
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1371 → 1514
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    7. XM_038624952.1 → XP_038480880.1  intersectin-2 isoform X5

      Conserved Domains (10) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      18687565..18789791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038560916.1 → XP_038416844.1  LOW QUALITY PROTEIN: intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NRR0, A0A8I3PP11, A0A8P0PAN5
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      18525190..18654045 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014120293.3 → XP_013975768.2  intersectin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RYE9, A0A8I3PP11, A0A8P0N6U4
      Conserved Domains (11) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1575 → 1709
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    2. XM_022404503.2 → XP_022260211.2  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NRR0, A0A8I3PP11, A0A8P0PAN5
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    3. XM_022404502.2 → XP_022260210.2  intersectin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RYS0, A0A8I3PKP1
      Conserved Domains (11) summary
      cd08375
      Location:1548 → 1682
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:754 → 810
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:895 → 946
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:978 → 1029
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1050 → 1108
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1123 → 1176
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:388 → 762
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1203 → 1386
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1405 → 1548
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    4. XM_014120296.3 → XP_013975771.2  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NRR0, A0A8I3PP11, A0A8P0PAN5
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    5. XM_022404504.2 → XP_022260212.2  intersectin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NRR0, A0A8I3PP11, A0A8P0PAN5
      Conserved Domains (11) summary
      PTZ00121
      Location:347 → 739
      PTZ00121; MAEBL; Provisional
      cd08375
      Location:1541 → 1675
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:747 → 803
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:888 → 939
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:971 → 1022
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1043 → 1101
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1116 → 1169
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1196 → 1379
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1398 → 1541
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    6. XM_014120297.3 → XP_013975772.2  intersectin-2 isoform X4

      UniProtKB/TrEMBL
      A0A8I3PKP1
      Conserved Domains (11) summary
      cd08375
      Location:1514 → 1648
      C2_Intersectin; C2 domain present in Intersectin
      smart00027
      Location:15 → 107
      EH; Eps15 homology domain
      cd11988
      Location:720 → 776
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:861 → 912
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:944 → 995
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1016 → 1074
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1089 → 1142
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      COG1196
      Location:354 → 728
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00160
      Location:1169 → 1352
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1371 → 1514
      PH_13; Pleckstrin homology domain
      cd21577
      Location:106 → 192
      KLF3_N; N-terminal domain of Kruppel-like factor 3

    7. XM_014120298.3 → XP_013975773.2  intersectin-2 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NNK7
      Conserved Domains (10) summary
      PTZ00121
      Location:381 → 773
      PTZ00121; MAEBL; Provisional
      smart00027
      Location:49 → 141
      EH; Eps15 homology domain
      cd11988
      Location:781 → 837
      SH3_Intersectin2_1; First Src homology 3 domain (or SH3A) of Intersectin-2
      cd11990
      Location:922 → 973
      SH3_Intersectin2_2; Second Src homology 3 domain (or SH3B) of Intersectin-2
      cd11992
      Location:1005 → 1056
      SH3_Intersectin2_3; Third Src homology 3 domain (or SH3C) of Intersectin-2
      cd11994
      Location:1077 → 1135
      SH3_Intersectin2_4; Fourth Src homology 3 domain (or SH3D) of Intersectin-2
      cd11996
      Location:1150 → 1203
      SH3_Intersectin2_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-2
      cd00160
      Location:1230 → 1413
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      pfam16652
      Location:1432 → 1575
      PH_13; Pleckstrin homology domain
      cd21577
      Location:140 → 226
      KLF3_N; N-terminal domain of Kruppel-like factor 3
    Nucleotide Protein
    Heading Accession and Version

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