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    EME1 essential meiotic structure-specific endonuclease 1 [ Gallus gallus (chicken) ]

    Gene ID: 422104, updated on 9-Mar-2024

    Summary

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    Symbol
    EME1provided by CGNC
    Full Name
    essential meiotic structure-specific endonuclease 1provided by CGNC
    Primary source
    CGNC:5797
    See related
    Ensembl:ENSGALG00010029654
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (11018769..11023583, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (10619184..10624000, complement)

    Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin Neighboring gene leucine rich repeat containing 59 Neighboring gene mitochondrial ribosomal protein L27 Neighboring gene uncharacterized LOC422106

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination. Kikuchi K, et al. Cancer Res, 2013 Jul 15. PMID 23576554, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic intra-S DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in replication fork processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in resolution of meiotic recombination intermediates IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Holliday junction resolvase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    crossover junction endonuclease EME1
    Names
    essential meiotic endonuclease 1 homolog 1 varinat 5
    XP_003642405.1
    XP_003642406.1
    XP_004946389.1
    XP_015151007.1
    XP_024997619.1
    XP_040542637.1
    XP_040542638.1
    XP_040542639.1
    XP_040542640.1
    XP_040542641.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      11018769..11023583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025141851.3 → XP_024997619.1  crossover junction endonuclease EME1 isoform X5

      UniProtKB/TrEMBL
      V5XZ07, V5Y129
      Related
      ENSGALP00010044389.1, ENSGALT00010071699.1
      Conserved Domains (1) summary
      cl41760
      Location:54 → 210
      XPF_nuclease-like; nuclease domain of XPF/MUS81 family proteins

    2. XM_003642358.5 → XP_003642406.1  crossover junction endonuclease EME1 isoform X4

      UniProtKB/TrEMBL
      V5Y027

    3. XM_003642357.5 → XP_003642405.1  crossover junction endonuclease EME1 isoform X3

      UniProtKB/TrEMBL
      A0A8V1AJR5, V5Y027
      Related
      ENSGALP00010044388.1, ENSGALT00010071698.1

    4. XM_015295521.3 → XP_015151007.1  crossover junction endonuclease EME1 isoform X2

      UniProtKB/TrEMBL
      V5Y027

    5. XM_004946332.4 → XP_004946389.1  crossover junction endonuclease EME1 isoform X1

      UniProtKB/TrEMBL
      V5Y027
      Related
      ENSGALP00010044391.1, ENSGALT00010071701.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      10619184..10624000 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040686707.2 → XP_040542641.1  crossover junction endonuclease EME1 isoform X5

      UniProtKB/TrEMBL
      V5XZ07, V5Y129
      Conserved Domains (1) summary
      cl41760
      Location:54 → 210
      XPF_nuclease-like; nuclease domain of XPF/MUS81 family proteins

    2. XM_040686706.2 → XP_040542640.1  crossover junction endonuclease EME1 isoform X4

      UniProtKB/TrEMBL
      V5Y027

    3. XM_040686705.2 → XP_040542639.1  crossover junction endonuclease EME1 isoform X3

      UniProtKB/TrEMBL
      V5Y027

    4. XM_040686704.2 → XP_040542638.1  crossover junction endonuclease EME1 isoform X2

      UniProtKB/TrEMBL
      V5Y027

    5. XM_040686703.2 → XP_040542637.1  crossover junction endonuclease EME1 isoform X1

      UniProtKB/TrEMBL
      V5Y027
    Nucleotide Protein Strain
    Heading Accession and Version

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