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    mvd mevalonate diphosphate decarboxylase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 394871, updated on 5-Mar-2024

    Summary

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    Official Symbol
    mvdprovided by Xenbase
    Official Full Name
    mevalonate diphosphate decarboxylaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-975218
    See related
    Ensembl:ENSXETG00000017427
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (66817108..66834522, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (69290449..69307581, complement)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene interleukin 17C Neighboring gene cytochrome b-245 alpha polypeptide Neighboring gene carbonic anhydrase VII Neighboring gene pyruvate dehyrogenase phosphatase catalytic subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables diphosphomevalonate decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cholesterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within isopentenyl diphosphate biosynthetic process, mevalonate pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    diphosphomevalonate decarboxylase
    Names
    mevalonate (diphospho) decarboxylase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      66817108..66834522 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004913561.4 → XP_004913618.2  diphosphomevalonate decarboxylase isoform X1

      UniProtKB/TrEMBL
      A0A6I8RS93, Q6P3Q0
      Related
      ENSXETP00000087830.2, ENSXETT00000093873.2
      Conserved Domains (1) summary
      cl28577
      Location:27 → 354
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]

    2. XM_004913565.4 → XP_004913622.3  diphosphomevalonate decarboxylase isoform X2

      UniProtKB/TrEMBL
      A0A8J0QYA9, Q6P3Q0
      Conserved Domains (1) summary
      cl28577
      Location:26 → 353
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]

    3. XM_004913562.4 → XP_004913619.2  diphosphomevalonate decarboxylase isoform X3

      UniProtKB/TrEMBL
      F6ZRK1, Q6P3Q0
      Conserved Domains (1) summary
      cl28577
      Location:4 → 331
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]

    4. XM_002941992.5 → XP_002942038.2  diphosphomevalonate decarboxylase isoform X3

      UniProtKB/TrEMBL
      F6ZRK1, Q6P3Q0
      Related
      ENSXETP00000037910.4, ENSXETT00000037910.5
      Conserved Domains (1) summary
      cl28577
      Location:4 → 331
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]

    5. XM_004913564.4 → XP_004913621.2  diphosphomevalonate decarboxylase isoform X3

      UniProtKB/TrEMBL
      F6ZRK1, Q6P3Q0
      Conserved Domains (1) summary
      cl28577
      Location:4 → 331
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]

    6. XM_004913563.4 → XP_004913620.2  diphosphomevalonate decarboxylase isoform X3

      UniProtKB/TrEMBL
      F6ZRK1, Q6P3Q0
      Conserved Domains (1) summary
      cl28577
      Location:4 → 331
      MVD1; Mevalonate pyrophosphate decarboxylase [Lipid transport and metabolism]
    Nucleotide Protein Strain
    Heading Accession and Version

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