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    SGMS1 sphingomyelin synthase 1 [ Bos taurus (cattle) ]

    Gene ID: 533538, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SGMS1provided by VGNC
    Official Full Name
    sphingomyelin synthase 1provided by VGNC
    Primary source
    VGNC:VGNC:34543
    See related
    BGD:BT27875; Ensembl:ENSBTAG00000011748
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 26
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (8700581..9024462, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene N-acylsphingosine amidohydrolase 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC104975938 Neighboring gene rab GTPase-activating protein 1-like Neighboring gene uncharacterized LOC132343935

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ceramide cholinephosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sphingomyelin synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingomyelin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylcholine:ceramide cholinephosphotransferase 1
    NP_001193064.1
    XP_005225446.1
    XP_005225447.1
    XP_005225448.1
    XP_005225453.1
    XP_005225455.1
    XP_005225456.1
    XP_005225459.1
    XP_024841438.1
    XP_024841439.1
    XP_024841443.1
    XP_024841444.1
    XP_024841446.1
    XP_024841454.1
    XP_024841459.1
    XP_024841475.1
    XP_024841476.1
    XP_059737867.1
    XP_059737869.1
    XP_059737870.1
    XP_059737871.1
    XP_059737872.1
    XP_059737873.1
    XP_059737874.1
    XP_059737875.1
    XP_059737876.1
    XP_059737877.1
    XP_059737878.1
    XP_059737879.1
    XP_059737880.1
    XP_059737881.1
    XP_059737882.1
    XP_059737883.1
    XP_059737884.1
    XP_059737885.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206135.2 → NP_001193064.1  phosphatidylcholine:ceramide cholinephosphotransferase 1

      See identical proteins and their annotated locations for NP_001193064.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000026
      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8700581..9024462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881886.1 → XP_059737869.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    2. XM_005225396.5 → XP_005225453.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225453.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    3. XM_005225390.4 → XP_005225447.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225447.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    4. XM_059881891.1 → XP_059737874.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    5. XM_059881890.1 → XP_059737873.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    6. XM_059881901.1 → XP_059737884.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    7. XM_059881900.1 → XP_059737883.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    8. XM_059881899.1 → XP_059737882.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    9. XM_024985691.2 → XP_024841459.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    10. XM_059881898.1 → XP_059737881.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    11. XM_005225391.5 → XP_005225448.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225448.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    12. XM_024985676.2 → XP_024841444.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    13. XM_024985678.2 → XP_024841446.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    14. XM_005225389.5 → XP_005225446.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225446.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    15. XM_024985670.2 → XP_024841438.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    16. XM_059881888.1 → XP_059737871.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    17. XM_024985671.2 → XP_024841439.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    18. XM_059881897.1 → XP_059737880.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    19. XM_059881893.1 → XP_059737876.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    20. XM_059881895.1 → XP_059737878.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    21. XM_059881896.1 → XP_059737879.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    22. XM_059881894.1 → XP_059737877.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    23. XM_059881892.1 → XP_059737875.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    24. XM_059881889.1 → XP_059737872.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    25. XM_059881884.1 → XP_059737867.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    26. XM_059881887.1 → XP_059737870.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    27. XM_024985686.2 → XP_024841454.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    28. XM_059881902.1 → XP_059737885.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31

    29. XM_005225399.5 → XP_005225456.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225456.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    30. XM_005225398.5 → XP_005225455.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225455.1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    31. XM_005225402.5 → XP_005225459.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_005225459.1

      UniProtKB/TrEMBL
      F1MF31
      Related
      ENSBTAP00000065438.1, ENSBTAT00000082007.2
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    32. XM_024985707.2 → XP_024841475.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    33. XM_024985708.2 → XP_024841476.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal

    34. XM_024985675.2 → XP_024841443.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

      UniProtKB/TrEMBL
      F1MF31
      Conserved Domains (2) summary
      cd09514
      Location:1 → 72
      SAM_SGMS1; SAM domain of sphingomyelin synthase
      pfam14360
      Location:276 → 349
      PAP2_C; PAP2 superfamily C-terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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