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    PLCD3 phospholipase C delta 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 490929, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PLCD3provided by VGNC
    Official Full Name
    phospholipase C delta 3provided by VGNC
    Primary source
    VGNC:VGNC:44648
    See related
    Ensembl:ENSCAFG00845006236
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 9
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (19073110..19092576)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (17784845..17804314)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (18286182..18305568)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (17951365..17970806)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (18130204..18149674)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene HEXIM P-TEFb complex subunit 2 Neighboring gene HEXIM P-TEFb complex subunit 1 Neighboring gene acyl-CoA binding domain containing 4 Neighboring gene N-myristoyltransferase 1 Neighboring gene dephospho-CoA kinase domain containing Neighboring gene uncharacterized LOC119873263

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
    XP_038341205.1
    XP_038341206.1
    XP_038341207.1
    XP_038402973.1
    XP_038402974.1
    XP_038466925.1
    XP_038466926.1
    XP_038466927.1
    XP_038484747.1
    XP_038484748.1
    XP_038484751.1
    XP_038532116.1
    XP_038532117.1
    XP_038532118.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      19073110..19092576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038676190.1 → XP_038532118.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MCX3, A0A8C0QY12, A0A8I3MYA9
      Related
      ENSCAFP00845008657.1, ENSCAFT00845011096.1
      Conserved Domains (4) summary
      cd08630
      Location:328 → 620
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:247 → 771
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:57 → 173
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:193 → 242
      EF-hand_10; EF hand

    2. XM_038676188.1 → XP_038532116.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0K9Y9
      Conserved Domains (4) summary
      cd00275
      Location:635 → 762
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 606
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16218
      Location:141 → 279
      EFh_PI-PLCdelta3; EF-hand motif found in phosphoinositide phospholipase C delta 3 (PI-PLC-delta3)

    3. XM_038676189.1 → XP_038532117.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K9Y9
      Conserved Domains (4) summary
      cd08630
      Location:291 → 583
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:210 → 734
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:156 → 205
      EF-hand_10; EF hand

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      17951365..17970806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038485279.1 → XP_038341207.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3

      Conserved Domains (4) summary
      cd08630
      Location:328 → 620
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:247 → 771
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:57 → 173
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:193 → 242
      EF-hand_10; EF hand

    2. XM_038485277.1 → XP_038341205.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      Conserved Domains (4) summary
      cd00275
      Location:635 → 762
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 606
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16218
      Location:141 → 279
      EFh_PI-PLCdelta3; EF-hand motif found in phosphoinositide phospholipase C delta 3 (PI-PLC-delta3)

    3. XM_038485278.1 → XP_038341206.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2

      Conserved Domains (4) summary
      cd08630
      Location:291 → 583
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:210 → 734
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:156 → 205
      EF-hand_10; EF hand

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      18130204..18149674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038610999.1 → XP_038466927.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3

      Conserved Domains (4) summary
      cd08630
      Location:328 → 620
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:247 → 771
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:57 → 173
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:193 → 242
      EF-hand_10; EF hand

    2. XM_038610997.1 → XP_038466925.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      Conserved Domains (4) summary
      cd00275
      Location:635 → 762
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 606
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16218
      Location:141 → 279
      EFh_PI-PLCdelta3; EF-hand motif found in phosphoinositide phospholipase C delta 3 (PI-PLC-delta3)

    3. XM_038610998.1 → XP_038466926.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2

      Conserved Domains (4) summary
      cd08630
      Location:291 → 583
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:210 → 734
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:156 → 205
      EF-hand_10; EF hand

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      18286182..18305568
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038547045.1 → XP_038402973.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MCX3, A0A8C0QY12, A0A8I3MYA9
      Conserved Domains (4) summary
      cd08630
      Location:328 → 620
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:247 → 771
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:57 → 173
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:193 → 242
      EF-hand_10; EF hand

    2. XM_038547046.1 → XP_038402974.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0K9Y9
      Conserved Domains (4) summary
      cd00275
      Location:635 → 762
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 606
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16218
      Location:141 → 279
      EFh_PI-PLCdelta3; EF-hand motif found in phosphoinositide phospholipase C delta 3 (PI-PLC-delta3)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      17784845..17804314
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038628823.1 → XP_038484751.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MCX3, A0A8C0QY12, A0A8I3MYA9
      Conserved Domains (4) summary
      cd08630
      Location:328 → 620
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:247 → 771
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:57 → 173
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:193 → 242
      EF-hand_10; EF hand

    2. XM_038628819.1 → XP_038484747.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0K9Y9
      Conserved Domains (4) summary
      cd00275
      Location:635 → 762
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08630
      Location:291 → 606
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16218
      Location:141 → 279
      EFh_PI-PLCdelta3; EF-hand motif found in phosphoinositide phospholipase C delta 3 (PI-PLC-delta3)

    3. XM_038628820.1 → XP_038484748.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K9Y9
      Conserved Domains (4) summary
      cd08630
      Location:291 → 583
      PI-PLCc_delta3; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3
      PLN02228
      Location:210 → 734
      PLN02228; Phosphoinositide phospholipase C
      cd13363
      Location:20 → 136
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      pfam14788
      Location:156 → 205
      EF-hand_10; EF hand
    Nucleotide Protein
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