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    ATG5 autophagy related 5 [ Gallus gallus (chicken) ]

    Gene ID: 421784, updated on 6-Jun-2024

    Summary

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    Official Symbol
    ATG5provided by CGNC
    Official Full Name
    autophagy related 5provided by CGNC
    Primary source
    CGNC:11461
    See related
    Ensembl:ENSGALG00010013247
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    APG5L
    Orthologs
    human mouse all
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    Genomic context

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    See ATG5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (67937240..68009125)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (67718832..67790798)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene absent in melanoma 1 Neighboring gene uncharacterized LOC107053080 Neighboring gene uncharacterized LOC107053079 Neighboring gene uncharacterized LOC121110218 Neighboring gene uncharacterized LOC121110217 Neighboring gene PR/SET domain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells. Liao Z, et al. In Vitro Cell Dev Biol Anim, 2019 May. PMID 31025250
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. All these findings indicated that Atg5 plays an important role in the proliferation of DF-1 cells.
      Title: Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in C-terminal protein lipidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to nitrogen starvation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Atg12-Atg5-Atg16 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in phagophore assembly site membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    autophagy protein 5
    Names
    ATG5 autophagy related 5 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006409.2 → NP_001006409.1  autophagy protein 5

      See identical proteins and their annotated locations for NP_001006409.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000065
      UniProtKB/TrEMBL
      A0A1D5PK91, A0A8V0YR58, Q5ZHW2
      Related
      ENSGALP00010018651.1, ENSGALT00010031847.1
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 270
      APG5; Autophagy protein Apg5

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      67937240..68009125
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046938875.1 → XP_046794831.1  autophagy protein 5 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YR58

    2. XM_046938874.1 → XP_046794830.1  autophagy protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YR53, F7AY48

    3. XM_046938873.1 → XP_046794829.1  autophagy protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PK91, A0A8V0YR58, Q5ZHW2

    4. XM_046938876.1 → XP_046794832.1  autophagy protein 5 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YR53

    5. XM_040697155.2 → XP_040553089.1  autophagy protein 5 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YR58

    6. XM_015284519.4 → XP_015140005.1  autophagy protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YR53, F7AY48
      Related
      ENSGALP00010018650.1, ENSGALT00010031846.1
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 244
      APG5; Autophagy protein Apg5

    7. XM_015284523.4 → XP_015140009.1  autophagy protein 5 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YJA5, A0A8V0YR58
      Related
      ENSGALP00010018644.1, ENSGALT00010031839.1
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 225
      APG5; Autophagy protein Apg5

    8. XM_015284520.4 → XP_015140006.1  autophagy protein 5 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJA5
      Related
      ENSGALP00010018646.1, ENSGALT00010031841.1
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 225
      APG5; Autophagy protein Apg5

    9. XM_015284521.4 → XP_015140007.1  autophagy protein 5 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YCX7
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 235
      APG5; Autophagy protein Apg5

    10. XM_015284518.4 → XP_015140004.1  autophagy protein 5 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YJA5
      Conserved Domains (1) summary
      pfam04106
      Location:72 → 218
      APG5; Autophagy protein Apg5

    11. XM_015284516.4 → XP_015140002.1  autophagy protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJA5
      Conserved Domains (1) summary
      pfam04106
      Location:79 → 225
      APG5; Autophagy protein Apg5

    12. XM_040697158.2 → XP_040553092.1  autophagy protein 5 isoform X13

      UniProtKB/TrEMBL
      A0A8V0YCX7

    13. XM_040697156.2 → XP_040553090.1  autophagy protein 5 isoform X11

      UniProtKB/TrEMBL
      A0A8V0YCX7

    14. XM_040697157.2 → XP_040553091.1  autophagy protein 5 isoform X10

    15. XM_046938877.1 → XP_046794833.1  autophagy protein 5 isoform X12

    RNA

    1. XR_006938655.1 RNA Sequence

    2. XR_006938656.1 RNA Sequence

    3. XR_003074222.3 RNA Sequence

    4. XR_001466036.4 RNA Sequence

    5. XR_001466037.4 RNA Sequence

    6. XR_003074223.3 RNA Sequence

    7. XR_003074224.3 RNA Sequence

    8. XR_005858085.2 RNA Sequence

    9. XR_003074225.3 RNA Sequence

    10. XR_005858086.2 RNA Sequence

    11. XR_003074226.3 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      67718832..67790798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046914040.1 → XP_046769996.1  autophagy protein 5 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YR58

    2. XM_046914037.1 → XP_046769993.1  autophagy protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YR53, F7AY48

    3. XM_046914034.1 → XP_046769990.1  autophagy protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PK91, A0A8V0YR58, Q5ZHW2

    4. XM_046914043.1 → XP_046769999.1  autophagy protein 5 isoform X9

      UniProtKB/TrEMBL
      A0A8V0YR53

    5. XM_046914039.1 → XP_046769995.1  autophagy protein 5 isoform X6

      UniProtKB/TrEMBL
      A0A8V0YR58

    6. XM_046914036.1 → XP_046769992.1  autophagy protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YR53, F7AY48

    7. XM_046914042.1 → XP_046769998.1  autophagy protein 5 isoform X8

      UniProtKB/TrEMBL
      A0A8V0YJA5, A0A8V0YR58

    8. XM_046914038.1 → XP_046769994.1  autophagy protein 5 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJA5

    9. XM_046914041.1 → XP_046769997.1  autophagy protein 5 isoform X7

      UniProtKB/TrEMBL
      A0A8V0YCX7

    10. XM_046914035.1 → XP_046769991.1  autophagy protein 5 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YJA5

    11. XM_046914033.1 → XP_046769989.1  autophagy protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJA5

    12. XM_046914044.1 → XP_046770000.1  autophagy protein 5 isoform X10

    RNA

    1. XR_006933963.1 RNA Sequence

    2. XR_006933964.1 RNA Sequence

    3. XR_006933954.1 RNA Sequence

    4. XR_006933953.1 RNA Sequence

    5. XR_006933956.1 RNA Sequence

    6. XR_006933955.1 RNA Sequence

    7. XR_006933958.1 RNA Sequence

    8. XR_006933957.1 RNA Sequence

    9. XR_006933959.1 RNA Sequence

    10. XR_006933960.1 RNA Sequence

    11. XR_006933961.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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