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    MGAT1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [ Bos taurus (cattle) ]

    Gene ID: 534248, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MGAT1provided by VGNC
    Official Full Name
    alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:54623
    See related
    BGD:BT17130; Ensembl:ENSBTAG00000001546
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GNT-1
    Orthologs
    human mouse all
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    Genomic context

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    See MGAT1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (39979967..39997282, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily A member 129 Neighboring gene uncharacterized LOC132345732 Neighboring gene olfactory receptor family 2 subfamily Y member 1 Neighboring gene uncharacterized LOC104969159 Neighboring gene ZFP62 zinc finger protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. N-acetylglucosaminyltransferase I activity of bovine oviduct epithelial cells: stimulation by luteinizing hormone, vascular endothelial growth factor and tumor necrosis factor alpha. Nozaki H, et al. J Reprod Dev, 2005 Apr. PMID 15699581
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-acetylglucosaminyltransferase I activity in the oviduct may contribute to the induction of glycosylation and thereby contributing to the provision of the optimal microenvironment for fertilization and early development of the embryos.
      Title: N-acetylglucosaminyltransferase I activity of bovine oviduct epithelial cells: stimulation by luteinizing hormone, vascular endothelial growth factor and tumor necrosis factor alpha.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
    Names
    N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I
    mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
    NP_001015653.1
    XP_005209264.1
    XP_024850144.1
    XP_059744261.1
    XP_059744262.1
    XP_059744263.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015653.1 → NP_001015653.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

      See identical proteins and their annotated locations for NP_001015653.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020936
      UniProtKB/TrEMBL
      Q5E9I4
      Related
      ENSBTAP00000095617.1, ENSBTAT00000100877.1
      Conserved Domains (1) summary
      cl11394
      Location:12 → 446
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      39979967..39997282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888278.1 → XP_059744261.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

      UniProtKB/TrEMBL
      Q5E9I4
      Related
      ENSBTAP00000103787.1, ENSBTAT00000135279.1

    2. XM_059888279.1 → XP_059744262.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

      UniProtKB/TrEMBL
      Q5E9I4

    3. XM_005209207.5 → XP_005209264.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

      See identical proteins and their annotated locations for XP_005209264.1

      UniProtKB/TrEMBL
      Q5E9I4
      Related
      ENSBTAP00000095829.1, ENSBTAT00000121252.1
      Conserved Domains (1) summary
      cl11394
      Location:12 → 446
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    4. XM_059888280.1 → XP_059744263.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

      UniProtKB/TrEMBL
      Q5E9I4

    5. XM_024994376.2 → XP_024850144.1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1

      UniProtKB/TrEMBL
      Q5E9I4
      Related
      ENSBTAP00000002024.4, ENSBTAT00000002024.6
      Conserved Domains (1) summary
      cl11394
      Location:12 → 446
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein Strain
    Heading Accession and Version

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