U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CNOT1 CCR4-NOT transcription complex subunit 1 [ Bos taurus (cattle) ]

    Gene ID: 533968, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CNOT1provided by VGNC
    Official Full Name
    CCR4-NOT transcription complex subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:27514
    See related
    BGD:BT27103; Ensembl:ENSBTAG00000020782
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 18
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (26304684..26387678, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene NDRG family member 4 Neighboring gene SET domain containing 6, protein lysine methyltransferase Neighboring gene small nucleolar RNA SNORA46 Neighboring gene small nucleolar RNA SNORA50 Neighboring gene solute carrier family 38 member 7 Neighboring gene glutamic-oxaloacetic transaminase 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    CCR4-NOT transcription complex subunit 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206039.1 → NP_001192968.1  CCR4-NOT transcription complex subunit 1

      See identical proteins and their annotated locations for NP_001192968.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      F1MHU9
      Conserved Domains (2) summary
      COG5103
      Location:840 → 2369
      CDC39; Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
      pfam16418
      Location:500 → 656
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      26304684..26387678 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024978374.2 → XP_024834142.1  CCR4-NOT transcription complex subunit 1 isoform X12

      Conserved Domains (2) summary
      pfam16418
      Location:464 → 627
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:817 → 2353
      Not1; CCR4-Not complex component, Not1

    2. XM_059876822.1 → XP_059732805.1  CCR4-NOT transcription complex subunit 1 isoform X14

    3. XM_024978373.2 → XP_024834141.1  CCR4-NOT transcription complex subunit 1 isoform X11

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 650
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:834 → 2363
      Not1; CCR4-Not complex component, Not1

    4. XM_005218666.5 → XP_005218723.1  CCR4-NOT transcription complex subunit 1 isoform X9

      See identical proteins and their annotated locations for XP_005218723.1

      Conserved Domains (2) summary
      COG5103
      Location:839 → 2368
      CDC39; Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
      pfam16418
      Location:500 → 656
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    5. XM_005218667.5 → XP_005218724.1  CCR4-NOT transcription complex subunit 1 isoform X10

      See identical proteins and their annotated locations for XP_005218724.1

      Conserved Domains (2) summary
      COG5103
      Location:835 → 2364
      CDC39; Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
      pfam16418
      Location:500 → 656
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    6. XM_005218664.5 → XP_005218721.1  CCR4-NOT transcription complex subunit 1 isoform X8

      See identical proteins and their annotated locations for XP_005218721.1

      Conserved Domains (2) summary
      COG5103
      Location:835 → 2371
      CDC39; Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
      pfam16418
      Location:500 → 656
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    7. XM_010814532.4 → XP_010812834.1  CCR4-NOT transcription complex subunit 1 isoform X7

      See identical proteins and their annotated locations for XP_010812834.1

      Related
      ENSBTAP00000027695.7, ENSBTAT00000027695.7
      Conserved Domains (2) summary
      COG5103
      Location:840 → 2376
      CDC39; Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
      pfam16418
      Location:500 → 656
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat

    8. XM_059876821.1 → XP_059732804.1  CCR4-NOT transcription complex subunit 1 isoform X13

    9. XM_024978371.2 → XP_024834139.1  CCR4-NOT transcription complex subunit 1 isoform X5

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:852 → 2381
      Not1; CCR4-Not complex component, Not1

    10. XM_024978368.2 → XP_024834136.1  CCR4-NOT transcription complex subunit 1 isoform X2

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:852 → 2388
      Not1; CCR4-Not complex component, Not1

    11. XM_024978372.2 → XP_024834140.1  CCR4-NOT transcription complex subunit 1 isoform X6

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:848 → 2377
      Not1; CCR4-Not complex component, Not1

    12. XM_024978369.2 → XP_024834137.1  CCR4-NOT transcription complex subunit 1 isoform X3

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:848 → 2384
      Not1; CCR4-Not complex component, Not1

    13. XM_024978370.2 → XP_024834138.1  CCR4-NOT transcription complex subunit 1 isoform X4

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:853 → 2382
      Not1; CCR4-Not complex component, Not1

    14. XM_024978367.2 → XP_024834135.1  CCR4-NOT transcription complex subunit 1 isoform X1

      Conserved Domains (2) summary
      pfam16418
      Location:500 → 663
      CNOT1_HEAT; CCR4-NOT transcription complex subunit 1 HEAT repeat
      cl26288
      Location:853 → 2389
      Not1; CCR4-Not complex component, Not1

    15. XM_059876820.1 → XP_059732803.1  CCR4-NOT transcription complex subunit 1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.