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    SPOPL speckle type BTB/POZ protein like [ Bos taurus (cattle) ]

    Gene ID: 510817, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SPOPLprovided by VGNC
    Official Full Name
    speckle type BTB/POZ protein likeprovided by VGNC
    Primary source
    VGNC:VGNC:35230
    See related
    BGD:BT21759; Ensembl:ENSBTAG00000013455
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (58559696..58612732, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107132265 Neighboring gene neurexophilin 2 Neighboring gene uncharacterized LOC112442641 Neighboring gene histone H3-like centromeric protein A Neighboring gene histamine N-methyltransferase Neighboring gene chromosome 15 open reading frame, human C11orf70 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    speckle-type POZ protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      58559696..58612732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878490.1 → XP_059734473.1  speckle-type POZ protein-like isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MAL9

    2. XM_005202525.5 → XP_005202582.1  speckle-type POZ protein-like isoform X3

      See identical proteins and their annotated locations for XP_005202582.1

      UniProtKB/TrEMBL
      A0A3Q1MAL9
      Conserved Domains (3) summary
      cd18343
      Location:179 → 301
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cd18519
      Location:297 → 392
      BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)
      cl02446
      Location:28 → 166
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

    3. XM_024980792.2 → XP_024836560.1  speckle-type POZ protein-like isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MAL9
      Conserved Domains (3) summary
      cd18343
      Location:179 → 301
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cd18519
      Location:297 → 392
      BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)
      cl02446
      Location:28 → 166
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

    4. XM_010802091.4 → XP_010800393.1  speckle-type POZ protein-like isoform X2

      See identical proteins and their annotated locations for XP_010800393.1

      UniProtKB/TrEMBL
      E1B7Y9
      Related
      ENSBTAP00000017898.3, ENSBTAT00000017898.4
      Conserved Domains (3) summary
      cd18343
      Location:200 → 322
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cl02446
      Location:49 → 187
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl28903
      Location:318 → 395
      BACK; BACK (BTB and C-terminal Kelch) domain

    5. XM_002685401.7 → XP_002685447.1  speckle-type POZ protein-like isoform X1

      See identical proteins and their annotated locations for XP_002685447.1

      UniProtKB/TrEMBL
      A0A3Q1M267
      Related
      ENSBTAP00000064093.1, ENSBTAT00000070707.2
      Conserved Domains (3) summary
      cd18343
      Location:200 → 322
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cd18519
      Location:318 → 413
      BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)
      cl02446
      Location:49 → 187
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

    6. XM_010802092.4 → XP_010800394.1  speckle-type POZ protein-like isoform X5

      See identical proteins and their annotated locations for XP_010800394.1

      Conserved Domains (2) summary
      cd18343
      Location:104 → 226
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cd18519
      Location:222 → 317
      BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)

    7. XM_024980798.2 → XP_024836566.1  speckle-type POZ protein-like isoform X4

      Conserved Domains (3) summary
      cd18343
      Location:200 → 322
      BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)
      cl02446
      Location:49 → 187
      MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
      cl28903
      Location:318 → 365
      BACK; BACK (BTB and C-terminal Kelch) domain

    RNA

    1. XR_009491688.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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