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    IGFBP2 insulin like growth factor binding protein 2 [ Ovis aries (sheep) ]

    Gene ID: 443469, updated on 5-Mar-2024

    Summary

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    Gene symbol
    IGFBP2
    Gene description
    insulin like growth factor binding protein 2
    See related
    EnsemblRapid:ENSOARG00020025420
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Also known as
    IGFBP-2
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See IGFBP2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (218627894..218657329)

    Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 Neighboring gene ribosomal protein L37a Neighboring gene insulin like growth factor binding protein 5 Neighboring gene uncharacterized LOC114113222 Neighboring gene transfer RNA cysteine (anticodon ACA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The characterization and expression of ovine insulin-like growth factor-binding protein-2. Delhanty PJ, et al. J Mol Endocrinol, 1992 Aug. PMID 1381182

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables insulin-like growth factor I binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables insulin-like growth factor II binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of insulin-like growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    insulin-like growth factor-binding protein 2
    Names
    IBP-2
    IGF-binding protein 2
    insulin-like growth factor binding protein 2, 36kDa
    insulin-like growth factor-binding protein-2, IGFBP-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009436.1 → NP_001009436.1  insulin-like growth factor-binding protein 2 precursor

      See identical proteins and their annotated locations for NP_001009436.1

      Status: PROVISIONAL

      Source sequence(s)
      S44612
      UniProtKB/Swiss-Prot
      Q29400
      UniProtKB/TrEMBL
      A0A836D668
      Related
      ENSOARP00020033046.1, ENSOART00020039880.2
      Conserved Domains (2) summary
      smart00121
      Location:37 → 124
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:219 → 298
      Thyroglobulin_1; Thyroglobulin type-1 repeat

    RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Genomic

    1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

      Range
      218627894..218657329
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29400.1 GenPept UniProtKB/Swiss-Prot:Q29400

    Gene LinkOut

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