Copg1 COPI coat complex subunit gamma 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Copg1provided by RGD
Official Full Name: COPI coat complex subunit gamma 1provided by RGD
Primary source: RGD:1565292
See related: Ensembl:ENSRNOG00000010474 AllianceGenome:RGD:1565292
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Copg
Summary: Predicted to enable structural molecule activity. Involved in establishment of Golgi localization and organelle transport along microtubule. Located in Golgi membrane. Orthologous to human COPG1 (COPI coat complex subunit gamma 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 370.9), Brain (RPKM 355.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q34

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (121923644..121949819)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (120366540..120392502)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (119815041..119840997)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

analysis of differential localization of coatomer complex isoforms within the Golgi apparatus
Title: Differential localization of coatomer complex isoforms within the Golgi apparatus.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in establishment of Golgi localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in organelle transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info
involved_in organelle transport along microtubule	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein secretion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of COPI vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
part_of COPI vesicle coat	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi membrane	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum-Golgi intermediate compartment	IBA Inferred from Biological aspect of Ancestor more info
part_of membrane coat	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: coatomer subunit gamma-1

Names: coatomer protein complex, subunit gamma 1; coatomer subunit gamma; gamma-1-COP; gamma-1-coat protein; gamma-COP; gamma-coat protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031822.4 → NP_001026992.1 coatomer subunit gamma-1

See identical proteins and their annotated locations for NP_001026992.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/Swiss-Prot

Q4AEF8

UniProtKB/TrEMBL

A0A8I5ZY43, A6IB29

Related

ENSRNOP00000084887.1, ENSRNOT00000110571.1

Conserved Domains (2) summary

COG5240
Location:7 → 869

SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]

sd00044
Location:398 → 423

HEAT; HEAT repeat [structural motif]