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COPG1 COPI coat complex subunit gamma 1 [ Homo sapiens (human) ]

Gene ID: 22820, updated on 13-Mar-2020

Summary

Official Symbol
COPG1provided by HGNC
Official Full Name
COPI coat complex subunit gamma 1provided by HGNC
Primary source
HGNC:HGNC:2236
See related
Ensembl:ENSG00000181789 MIM:615525
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
COPG
Expression
Ubiquitous expression in thyroid (RPKM 47.3), prostate (RPKM 41.1) and 25 other tissues See more
Orthologs

Genomic context

See COPG1 in Genome Data Viewer
Location:
3q21.3
Exon count:
25
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (129249575..129277773)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (128968453..128996616)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 pseudogene 12 Neighboring gene uncharacterized LOC105374102 Neighboring gene microRNA 6826 Neighboring gene 5-hydroxymethylcytosine binding, ES cell specific Neighboring gene H1-10 antisense RNA 1 Neighboring gene H1.10 linker histone

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21068

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ER to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ER to Golgi vesicle-mediated transport TAS
Traceable Author Statement
more info
 
establishment of Golgi localization ISS
Inferred from Sequence or Structural Similarity
more info
 
intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
organelle transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organelle transport along microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 
protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
retrograde vesicle-mediated transport, Golgi to ER TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
COPI vesicle coat ISS
Inferred from Sequence or Structural Similarity
more info
 
Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
Golgi membrane TAS
Traceable Author Statement
more info
 
cell IEA
Inferred from Electronic Annotation
more info
 
cytosol TAS
Traceable Author Statement
more info
 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transport vesicle TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
coatomer subunit gamma-1
Names
coat protein gamma-cop
coatomer protein complex subunit gamma 1
coatomer protein complex, subunit gamma
coatomer subunit gamma
gamma-1-COP
gamma-1-coat protein
gamma-COP
gamma-coat protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016128.4NP_057212.1  coatomer subunit gamma-1

    See identical proteins and their annotated locations for NP_057212.1

    Status: VALIDATED

    Source sequence(s)
    AB047846, AC137695, AK025147, BU521557
    Consensus CDS
    CCDS33851.1
    UniProtKB/Swiss-Prot
    Q9Y678
    Related
    ENSP00000325002.6, ENST00000314797.10
    Conserved Domains (2) summary
    COG5240
    Location:7869
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    sd00044
    Location:398423
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    129249575..129277773
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512549.2XP_011510851.1  coatomer subunit gamma-1 isoform X1

    Conserved Domains (2) summary
    pfam01602
    Location:23520
    Adaptin_N; Adaptin N terminal region
    sd00044
    Location:398423
    HEAT; HEAT repeat [structural motif]
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