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    BRCC3 BRCA1/BRCA2-containing complex subunit 3 [ Sus scrofa (pig) ]

    Gene ID: 100516948, updated on 8-Mar-2024

    Summary

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    Official Symbol
    BRCC3provided by VGNC
    Official Full Name
    BRCA1/BRCA2-containing complex subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:85870
    See related
    Ensembl:ENSSSCG00000012813
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    BRCC36
    Expression
    Ubiquitous expression in spleen (RPKM 11.2), ovary (RPKM 9.6) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See BRCC3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (125383392..125439082)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (142991891..143046729, complement)

    Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene FUN14 domain containing 2 Neighboring gene mature T cell proliferation 1 Neighboring gene C-X9-C motif containing 4 Neighboring gene phosphatidylinositol-binding clathrin assembly protein-like Neighboring gene VHL binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables polyubiquitin modification-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BRCA1-A complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of BRISC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lys-63-specific deubiquitinase BRCC36
    NP_001229952.1
    XP_020935130.1
    XP_020935131.1
    XP_020935133.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243023.1 → NP_001229952.1  lys-63-specific deubiquitinase BRCC36

      Status: VALIDATED

      Source sequence(s)
      CK451567, CN154900, DN103673, FS665195
      UniProtKB/TrEMBL
      A0A287AFB6, A0A480V5W3, A0A4X1T8A2, A0A8D1GVE9
      Related
      ENSSSCP00000042713.2, ENSSSCT00000058083.3
      Conserved Domains (1) summary
      cd08068
      Location:13 → 267
      MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

      Range
      125383392..125439082
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021079471.1 → XP_020935130.1  lys-63-specific deubiquitinase BRCC36 isoform X1

      UniProtKB/TrEMBL
      A0A5G2QUJ6, A0A8D0NLK1
      Related
      ENSSSCP00000067829.1, ENSSSCT00000068535.2
      Conserved Domains (1) summary
      cd08068
      Location:13 → 292
      MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

    2. XM_021079472.1 → XP_020935131.1  lys-63-specific deubiquitinase BRCC36 isoform X2

      UniProtKB/TrEMBL
      A0A5G2QTC9, A0A8D0VG52
      Related
      ENSSSCP00000068088.1, ENSSSCT00000075540.2
      Conserved Domains (1) summary
      cd08068
      Location:13 → 268
      MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

    3. XM_021079474.1 → XP_020935133.1  lys-63-specific deubiquitinase BRCC36 isoform X3

      UniProtKB/TrEMBL
      A0A4X1T957, A0A8D2BC76
      Conserved Domains (1) summary
      cd08068
      Location:13 → 243
      MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
    Nucleotide Protein
    Heading Accession and Version

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