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| Status |
Public on Oct 19, 2010 |
| Title |
Gene expression in adipose, liver and skeletal muscle of mice fed a diet with c9, t11 conjugated linoleic acid enriched beef |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Conjugated Linoleic Acid (CLA) is a collective term for the positional and geometric isomers of linoleic acid. In recent years CLA has been reported to have anti-carcinogenic, anti-obesity, anti-inflammatory and anti-artherogenic effects. The aim of this study was to determine the effects of a natural high-CLA enriched beef source on three primary insulin responsive tissues: adipose, liver and skeletal muscle.
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| Overall design |
ob/ob mice were assigned to one of two diets: a control beef diet, low in c9, t11-CLA (control diet) or a c9, t11-CLA enriched beef diet. After a 28 day feeding trial, RNA was extracted from adipose, liver and skeletal muscle tissue and hybridized to Affymetrix microarrays.
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| Contributor(s) |
Roche HM |
| Citation(s) |
20929581 |
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| Submission date |
Jul 30, 2010 |
| Last update date |
Apr 08, 2013 |
| Contact name |
Helen M Roche |
| E-mail(s) |
helen.roche@ucd.ie
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| Organization name |
University College Dublin
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| Lab |
Nutrigenomics Research Group
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| Street address |
UCD Conway Institute of Biomolecular and Biomedical Research
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| City |
Dublin |
| State/province |
Belfield |
| ZIP/Postal code |
Dublin 4 |
| Country |
Ireland |
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| Platforms (1) |
| GPL7440 |
NuGO array (mouse) NuGO_Mm1a520177 |
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| Samples (39)
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| GSM572699 |
Adipose tissue, control diet, biological replicate 1 |
| GSM572700 |
Adipose tissue, control diet, biological replicate 2 |
| GSM572701 |
Adipose tissue, control diet, biological replicate 3 |
| GSM572702 |
Adipose tissue, control diet, biological replicate 4 |
| GSM572703 |
Adipose tissue, control diet, biological replicate 5 |
| GSM572704 |
Adipose tissue, control diet, biological replicate 6 |
| GSM572705 |
Adipose tissue, control diet, biological replicate 7 |
| GSM572706 |
Adipose tissue, high-CLA beef diet, biological replicate 1 |
| GSM572707 |
Adipose tissue, high-CLA beef diet, biological replicate 2 |
| GSM572708 |
Adipose tissue, high-CLA beef diet, biological replicate 3 |
| GSM572709 |
Adipose tissue, high-CLA beef diet, biological replicate 4 |
| GSM572710 |
Adipose tissue, high-CLA beef diet, biological replicate 5 |
| GSM572711 |
Adipose tissue, high-CLA beef diet, biological replicate 6 |
| GSM572712 |
Muscle tissue, control diet, biological replicate 1 |
| GSM572713 |
Muscle tissue, control diet, biological replicate 2 |
| GSM572714 |
Muscle tissue, control diet, biological replicate 3 |
| GSM572715 |
Muscle tissue, control diet, biological replicate 4 |
| GSM572716 |
Muscle tissue, control diet, biological replicate 5 |
| GSM572717 |
Muscle tissue, control diet, biological replicate 6 |
| GSM572718 |
Muscle tissue, high-CLA diet, biological replicate 1 |
| GSM572719 |
Muscle tissue, high-CLA diet, biological replicate 2 |
| GSM572720 |
Muscle tissue, high-CLA diet, biological replicate 3 |
| GSM572721 |
Muscle tissue, high-CLA diet, biological replicate 4 |
| GSM572722 |
Muscle tissue, high-CLA diet, biological replicate 5 |
| GSM572723 |
Muscle tissue, high-CLA diet, biological replicate 6 |
| GSM572724 |
Liver tissue, control diet, biological replicate 1 |
| GSM572725 |
Liver tissue, control diet, biological replicate 2 |
| GSM572726 |
Liver tissue, control diet, biological replicate 3 |
| GSM572727 |
Liver tissue, control diet, biological replicate 4 |
| GSM572728 |
Liver tissue, control diet, biological replicate 5 |
| GSM572729 |
Liver tissue, control diet, biological replicate 6 |
| GSM572730 |
Liver tissue, control diet, biological replicate 7 |
| GSM572731 |
Liver tissue, high-CLA diet, biological replicate 1 |
| GSM572732 |
Liver tissue, high-CLA diet, biological replicate 2 |
| GSM572733 |
Liver tissue, high-CLA diet, biological replicate 3 |
| GSM572734 |
Liver tissue, high-CLA diet, biological replicate 4 |
| GSM572735 |
Liver tissue, high-CLA diet, biological replicate 5 |
| GSM572736 |
Liver tissue, high-CLA diet, biological replicate 6 |
| GSM572737 |
Liver tissue, high-CLA diet, biological replicate 7 |
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| Relations |
| BioProject |
PRJNA131221 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE23337_RAW.tar |
76.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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