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    STYX serine/threonine/tyrosine interacting protein [ Bos taurus (cattle) ]

    Gene ID: 616825, updated on 5-Mar-2024

    Summary

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    Official Symbol
    STYXprovided by VGNC
    Official Full Name
    serine/threonine/tyrosine interacting proteinprovided by VGNC
    Primary source
    VGNC:VGNC:35452
    See related
    BGD:BT25596; Ensembl:ENSBTAG00000046956
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (11353165..11460248, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene thrombospondin 4 Neighboring gene metaxin 3 Neighboring gene serine incorporator 5 Neighboring gene glucosamine-phosphate N-acetyltransferase 1 Neighboring gene proteasome 26S subunit, ATPase 6 Neighboring gene endoplasmic reticulum oxidoreductase 1 alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables F-box domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine/tyrosine-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193128.1 → NP_001180057.1  serine/threonine/tyrosine-interacting protein

      See identical proteins and their annotated locations for NP_001180057.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000010
      UniProtKB/TrEMBL
      G3MYQ0
      Related
      ENSBTAP00000054687.1, ENSBTAT00000063138.3
      Conserved Domains (1) summary
      cd14522
      Location:25 → 175
      DSP_STYX; dual specificity phosphatase-like domain of serine/threonine/tyrosine-interacting protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11353165..11460248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059890655.1 → XP_059746638.1  serine/threonine/tyrosine-interacting protein isoform X2

    2. XM_024997832.2 → XP_024853600.1  serine/threonine/tyrosine-interacting protein isoform X1

      Related
      ENSBTAP00000103496.1, ENSBTAT00000114669.1
      Conserved Domains (1) summary
      cd00127
      Location:28 → 171
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...

    3. XM_059890657.1 → XP_059746640.1  serine/threonine/tyrosine-interacting protein isoform X3

    4. XM_059890656.1 → XP_059746639.1  serine/threonine/tyrosine-interacting protein isoform X3

    5. XM_024997833.2 → XP_024853601.1  serine/threonine/tyrosine-interacting protein isoform X5

      Related
      ENSBTAP00000102897.1, ENSBTAT00000112445.1
      Conserved Domains (1) summary
      cd00127
      Location:28 → 171
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...

    6. XM_005211397.5 → XP_005211454.1  serine/threonine/tyrosine-interacting protein isoform X4

      See identical proteins and their annotated locations for XP_005211454.1

      Related
      ENSBTAP00000097988.1, ENSBTAT00000111551.1
      Conserved Domains (1) summary
      cd14522
      Location:25 → 158
      DSP_STYX; dual specificity phosphatase-like domain of serine/threonine/tyrosine-interacting protein

    RNA

    1. XR_003036698.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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