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    NOX3 NADPH oxidase 3 [ Bos taurus (cattle) ]

    Gene ID: 526999, updated on 5-Mar-2024

    Summary

    Official Symbol
    NOX3provided by VGNC
    Official Full Name
    NADPH oxidase 3provided by VGNC
    Primary source
    VGNC:VGNC:32183
    See related
    Ensembl:ENSBTAG00000013551
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    Location:
    chromosome: 9
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (91998779..92064844, complement)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346141 Neighboring gene transcription factor B1, mitochondrial Neighboring gene claudin 20 Neighboring gene uncharacterized LOC132346142 Neighboring gene hydroxyacyl-coenzyme A dehydrogenase, mitochondrial-like Neighboring gene uncharacterized LOC112448086

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables superoxide-generating NAD(P)H oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191333.1NP_001178262.1  NADPH oxidase 3

      See identical proteins and their annotated locations for NP_001178262.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000009
      UniProtKB/TrEMBL
      E1BFF3
      Related
      ENSBTAP00000018021.4, ENSBTAT00000018021.5
      Conserved Domains (2) summary
      cd06186
      Location:293566
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      pfam01794
      Location:66217
      Ferric_reduct; Ferric reductase like transmembrane component

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      91998779..92064844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)