RAB8A RAB8A, member RAS oncogene family [Gallus gallus (chicken)] - Gene

Summary

Symbol: RAB8Aprovided by CGNC
Full Name: RAB8A, member RAS oncogene familyprovided by CGNC
Primary source: CGNC:66558
See related: Ensembl:ENSGALG00010027956
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 28

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	28	NC_052559.1 (4870604..4878449, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	28	NC_052600.1 (4432888..4440734, complement)

Chromosome 28 - NC_052559.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Golgi vesicle fusion to target membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neurotransmitter receptor transport to postsynaptic membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein localization to plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of exocytosis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vesicle docking involved in exocytosis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in dendritic spine	IEA Inferred from Electronic Annotation more info	PubMed
located_in endosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in synaptic vesicle	IEA Inferred from Electronic Annotation more info	PubMed
located_in trans-Golgi network transport vesicle	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ras-related protein Rab-8A

NP_001384253.1

EC 3.6.5.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001397324.1 → NP_001384253.1 ras-related protein Rab-8A

Status: VALIDATED

Source sequence(s)

JAENSK010000376

UniProtKB/Swiss-Prot

Q5F470

UniProtKB/TrEMBL

A0A8V1A6G3

Related

ENSGALP00010041507.1, ENSGALT00010067764.1

Conserved Domains (1) summary

cd01867
Location:6 → 172

Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052559.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4870604..4878449 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052600.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

4432888..4440734 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001031504.1: Suppressed sequence

Description

NM_001031504.1: This RefSeq was removed because it represents a rare readthrough transcript between TPM4 and RAB8A.