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    B2M beta-2-microglobulin [ Sus scrofa (pig) ]

    Gene ID: 110255236, updated on 15-Mar-2024

    Summary

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    Official Symbol
    B2Mprovided by VGNC
    Official Full Name
    beta-2-microglobulinprovided by VGNC
    Primary source
    VGNC:VGNC:110573
    See related
    Ensembl:ENSSSCG00000004687
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in spleen (RPKM 2778.6), lung (RPKM 2465.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (126837721..126844043, complement)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene telomere repeat binding bouquet formation protein 2 Neighboring gene uncharacterized protein C12orf31 homolog pseudogene Neighboring gene tripartite motif containing 69 Neighboring gene uncharacterized LOC110261204 Neighboring gene beta-2-microglobulin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_010443.5 Chromosome 1 Reference Sscrofa11.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR. Nygard AB, et al. BMC Mol Biol, 2007 Aug 15. PMID 17697375, Free PMC Article
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MHC class II protein complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immunoglobulin production involved in immunoglobulin-mediated immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptide antigen assembly with MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MHC class I protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-2-microglobulin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      126837721..126844043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021096362.1 → XP_020952021.1  beta-2-microglobulin

      UniProtKB/Swiss-Prot
      Q07717, Q8WN08
      UniProtKB/TrEMBL
      A0A5S6FYV9, B2NJ26
      Related
      ENSSSCP00000052369.2, ENSSSCT00000061969.2
      Conserved Domains (1) summary
      cd05770
      Location:24 → 115
      IgC_beta2m; Class I major histocompatibility complex (MHC) beta2-microglobulin

    RNA

    1. XR_002345114.1 RNA Sequence

    2. XR_002345118.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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