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    HYAL1 hyaluronidase 1 [ Bos taurus (cattle) ]

    Gene ID: 515397, updated on 3-Apr-2024

    Summary

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    Gene symbol
    HYAL1
    Gene description
    hyaluronidase 1
    See related
    BGD:BT29234
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50029843..50032902)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene Ras association domain family member 1 Neighboring gene tumor suppressor 2, mitochondrial calcium regulator Neighboring gene hyaluronidase 2 Neighboring gene N-alpha-acetyltransferase 80, NatH catalytic subunit Neighboring gene hyaluronidase 3 Neighboring gene interferon related developmental regulator 2 Neighboring gene leucine rich single-pass membrane protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improvement of the digestibility of sulfated hyaluronans by bovine testicular hyaluronidase: a UV spectroscopic and mass spectrometric study. Lemmnitzer K, et al. Biomed Res Int, 2014. PMID 24971366, Free PMC Article
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study focuses on the investigation of the digestibility of glycosaminoglycans with different degrees of sulfation by bovine testicular hyaluronidase.
      Title: Improvement of the digestibility of sulfated hyaluronans by bovine testicular hyaluronidase: a UV spectroscopic and mass spectrometric study.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hyalurononglucosaminidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hyaluronan catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hyaluronidase-1
    Names
    hyal-1
    hyaluronoglucosaminidase 1
    NP_001017941.1
    XP_024838438.1
    XP_059735621.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017941.1 → NP_001017941.1  hyaluronidase-1 precursor

      See identical proteins and their annotated locations for NP_001017941.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021035
      UniProtKB/Swiss-Prot
      Q3T0A8, Q5E985, Q5E9Z4
      UniProtKB/TrEMBL
      F1MSK8
      Conserved Domains (1) summary
      pfam01630
      Location:40 → 366
      Glyco_hydro_56; Hyaluronidase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50029843..50032902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879638.1 → XP_059735621.1  hyaluronidase-1 isoform X1

    2. XM_024982670.2 → XP_024838438.1  hyaluronidase-1 isoform X2

      Conserved Domains (1) summary
      pfam01630
      Location:40 → 345
      Glyco_hydro_56; Hyaluronidase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E985.1 GenPept UniProtKB/Swiss-Prot:Q5E985

    Gene LinkOut

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