U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PFKM phosphofructokinase, muscle [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100345647, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PFKM
    Gene description
    phosphofructokinase, muscle
    See related
    Ensembl:ENSOCUG00000017445
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    PFK; PFK-A; PFK-M; ATP-PFK
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 8
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 8 NC_067381.1 (111767301..111801291)

    Chromosome 8 - NC_067381.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 2 Neighboring gene collagen type II alpha 1 chain Neighboring gene SUMO specific peptidase 1 Neighboring gene ankyrin repeat and SOCS box containing 8 Neighboring gene coiled-coil domain containing 184

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_067381.1 Chromosome 8 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism. Šmerc A, et al. PLoS One, 2011 May 4. PMID 21573193, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Posttranslational modification of PFK1 enzyme might be the pivotal factor of deregulated glycolytic flux in tumors.
      Title: Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 6-phosphofructokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables AMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructose-6-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monosaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical glycolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 1,6-bisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of 6-phosphofructokinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ATP-dependent 6-phosphofructokinase, muscle type
    Names
    6-phosphofructokinase type A
    Phosphofructo-1-kinase isozyme A
    Phosphohexokinase

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067381.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      111767301..111801291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_051850440.1 → XP_051706400.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    2. XM_051850433.1 → XP_051706393.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X1

      UniProtKB/TrEMBL
      A0A5F9DGX0

    3. XM_051850434.1 → XP_051706394.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X2

    4. XM_051850436.1 → XP_051706396.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    5. XM_051850438.1 → XP_051706398.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    6. XM_051850437.1 → XP_051706397.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    7. XM_051850435.1 → XP_051706395.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    8. XM_051850439.1 → XP_051706399.1  ATP-dependent 6-phosphofructokinase, muscle type isoform X3

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P00511.3 GenPept UniProtKB/Swiss-Prot:P00511

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.