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    ELMO1 engulfment and cell motility 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 612913, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ELMO1provided by VGNC
    Official Full Name
    engulfment and cell motility 1provided by VGNC
    Primary source
    VGNC:VGNC:40309
    See related
    Ensembl:ENSCAFG00845029636
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 14
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (48104763..48631432, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (47606767..48132630, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (48267197..48792889, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (48210909..48736343, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (47890268..48416690, complement)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene microtubule associated tyrosine carboxypeptidase 2 Neighboring gene anillin, actin binding protein Neighboring gene acyloxyacyl hydrolase Neighboring gene uncharacterized LOC111098824 Neighboring gene uncharacterized LOC111098825 Neighboring gene 40S ribosomal protein S21-like Neighboring gene THAP domain containing 5 Neighboring gene G protein-coupled receptor 141 Neighboring gene DnaJ heat shock protein family (Hsp40) member B9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of guanyl-nucleotide exchange factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    engulfment and cell motility protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      48104763..48631432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686968.1 → XP_038542896.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0YXZ2, A0A8I3Q211, A0A8P0SZB6
      Related
      ENSCAFP00845041186.1, ENSCAFT00845052495.1
      Conserved Domains (4) summary
      cd13359
      Location:611 → 740
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:368 → 546
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:166 → 344
      DUF3361; Domain of unknown function (DUF3361)
      cl28922
      Location:70 → 155
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_038686970.1 → XP_038542898.1  engulfment and cell motility protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q838, A0A8I3Q865, A0A8P0P102, A0A8P0T4B1
      Related
      ENSCAFP00845041235.1, ENSCAFT00845052547.1
      Conserved Domains (3) summary
      cd13359
      Location:561 → 690
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:318 → 496
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 294
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_038686969.1 → XP_038542897.1  engulfment and cell motility protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JZI3, A0A8I3Q211, A0A8P0SZB6
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    4. XM_038686971.1 → XP_038542899.1  engulfment and cell motility protein 1 isoform X4

      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      48210909..48736343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038495069.1 → XP_038350997.1  engulfment and cell motility protein 1 isoform X1

      Conserved Domains (4) summary
      cd13359
      Location:611 → 740
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:368 → 546
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:166 → 344
      DUF3361; Domain of unknown function (DUF3361)
      cl28922
      Location:70 → 155
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_038495071.1 → XP_038350999.1  engulfment and cell motility protein 1 isoform X3

      Conserved Domains (3) summary
      cd13359
      Location:561 → 690
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:318 → 496
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 294
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_038495070.1 → XP_038350998.1  engulfment and cell motility protein 1 isoform X2

      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    4. XM_038495072.1 → XP_038351000.1  engulfment and cell motility protein 1 isoform X4

      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      47890268..48416690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038621283.1 → XP_038477211.1  engulfment and cell motility protein 1 isoform X1

      Conserved Domains (4) summary
      cd13359
      Location:611 → 740
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:368 → 546
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:166 → 344
      DUF3361; Domain of unknown function (DUF3361)
      cl28922
      Location:70 → 155
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_038621285.1 → XP_038477213.1  engulfment and cell motility protein 1 isoform X3

      Conserved Domains (3) summary
      cd13359
      Location:561 → 690
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:318 → 496
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 294
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_038621284.1 → XP_038477212.1  engulfment and cell motility protein 1 isoform X2

      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    4. XM_038621286.1 → XP_038477214.1  engulfment and cell motility protein 1 isoform X4

      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      48267197..48792889 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038557346.1 → XP_038413274.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0YXZ2, A0A8I3Q211, A0A8P0SZB6
      Conserved Domains (4) summary
      cd13359
      Location:611 → 740
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:368 → 546
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:166 → 344
      DUF3361; Domain of unknown function (DUF3361)
      cl28922
      Location:70 → 155
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_038557348.1 → XP_038413276.1  engulfment and cell motility protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q838, A0A8I3Q865, A0A8P0P102, A0A8P0T4B1
      Conserved Domains (3) summary
      cd13359
      Location:561 → 690
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:318 → 496
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 294
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_038557347.1 → XP_038413275.1  engulfment and cell motility protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JZI3, A0A8I3Q211, A0A8P0SZB6
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    4. XM_038557349.1 → XP_038413277.1  engulfment and cell motility protein 1 isoform X4

      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47606767..48132630 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038440949.1 → XP_038296877.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0YXZ2, A0A8I3Q211, A0A8P0SZB6
      Conserved Domains (4) summary
      cd13359
      Location:611 → 740
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:368 → 546
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:166 → 344
      DUF3361; Domain of unknown function (DUF3361)
      cl28922
      Location:70 → 155
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_022427578.2 → XP_022283286.1  engulfment and cell motility protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q838, A0A8I3Q865, A0A8P0P102, A0A8P0T4B1
      Conserved Domains (3) summary
      cd13359
      Location:561 → 690
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:318 → 496
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 294
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_014119052.1 → XP_013974527.1  engulfment and cell motility protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0JZI3, A0A8I3Q211, A0A8P0SZB6
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    4. XM_005628727.4 → XP_005628784.1  engulfment and cell motility protein 1 isoform X4

      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
    Nucleotide Protein
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