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    Odf2l outer dense fiber of sperm tails 2-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685425, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Odf2lprovided by RGD
    Official Full Name
    outer dense fiber of sperm tails 2-likeprovided by RGD
    Primary source
    RGD:1593831
    See related
    Ensembl:ENSRNOG00000014059 AllianceGenome:RGD:1593831
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308397
    Summary
    Predicted to be involved in negative regulation of cilium assembly. Predicted to be located in centriolar satellite. Predicted to be active in centrosome and ciliary basal body. Orthologous to human ODF2L (outer dense fiber of sperm tails 2 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 28.7), Testes (RPKM 25.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    2q44
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (236696158..236733090)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (234036049..234072751)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (250995018..251032908)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485995 Neighboring gene chloride channel accessory 2 Neighboring gene collagen type XXIV alpha 1 chain Neighboring gene uncharacterized LOC134485997 Neighboring gene uncharacterized LOC134485996

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of BCAP, a new protein associated with basal bodies and centrioles. Ponsard C, et al. Front Biosci, 2007 May 1. PMID 17485331
    2. BCAP is a centriolar satellite protein and inhibitor of ciliogenesis. de Saram P, et al. J Cell Sci, 2017 Oct 1. PMID 28775150
    3. The novel testicular enrichment protein Cfap58 is required for Notch-associated ciliogenesis. Li ZZ, et al. Biosci Rep, 2020 Jan 31. PMID 31904090, Free PMC Article
    4. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein BCAP
    Names
    outer dense fiber protein 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134708.1 → NP_001128180.1  protein BCAP

      See identical proteins and their annotated locations for NP_001128180.1

      Status: VALIDATED

      Source sequence(s)
      BC166823, CB767200
      UniProtKB/TrEMBL
      A0A8I6GC60, A6HWA7
      Conserved Domains (1) summary
      pfam06156
      Location:292 → 372
      DUF972; Protein of unknown function (DUF972)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      236696158..236733090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233447.5 → XP_006233509.1  protein BCAP isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZXN4, A0A8I6GC60
      Related
      ENSRNOP00000083735.1
      Conserved Domains (1) summary
      pfam06156
      Location:317 → 397
      DUF972; Protein of unknown function (DUF972)

    2. XM_006233440.5 → XP_006233502.1  protein BCAP isoform X1

      See identical proteins and their annotated locations for XP_006233502.1

      UniProtKB/TrEMBL
      A0A8I6GC60
      Conserved Domains (1) summary
      pfam06156
      Location:317 → 397
      DUF972; Protein of unknown function (DUF972)

    3. XM_017591110.3 → XP_017446599.1  protein BCAP isoform X2

      UniProtKB/TrEMBL
      A0A8I6GC60
      Related
      ENSRNOP00000084766.1
      Conserved Domains (1) summary
      pfam06156
      Location:312 → 392
      DUF972; Protein of unknown function (DUF972)

    4. XM_006233439.5 → XP_006233501.1  protein BCAP isoform X1

      See identical proteins and their annotated locations for XP_006233501.1

      UniProtKB/TrEMBL
      A0A8I6GC60
      Conserved Domains (1) summary
      pfam06156
      Location:317 → 397
      DUF972; Protein of unknown function (DUF972)

    5. XM_039103138.2 → XP_038959066.1  protein BCAP isoform X9

      Conserved Domains (1) summary
      COG1196
      Location:71 → 455
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    6. XM_039103139.2 → XP_038959067.1  protein BCAP isoform X10

      Conserved Domains (1) summary
      COG1196
      Location:210 → 497
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    7. XM_063282552.1 → XP_063138622.1  protein BCAP isoform X4

    8. XM_006233441.5 → XP_006233503.1  protein BCAP isoform X1

      See identical proteins and their annotated locations for XP_006233503.1

      UniProtKB/TrEMBL
      A0A8I6GC60
      Conserved Domains (1) summary
      pfam06156
      Location:317 → 397
      DUF972; Protein of unknown function (DUF972)

    9. XM_063282553.1 → XP_063138623.1  protein BCAP isoform X6

    10. XM_006233445.5 → XP_006233507.1  protein BCAP isoform X3

      See identical proteins and their annotated locations for XP_006233507.1

      UniProtKB/TrEMBL
      A0A0G2K7F1, A0A8I6GC60, A6HWA6
      Related
      ENSRNOP00000074178.1
      Conserved Domains (1) summary
      COG1196
      Location:193 → 577
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    11. XM_063282555.1 → XP_063138625.1  protein BCAP isoform X7

    12. XM_063282556.1 → XP_063138626.1  protein BCAP isoform X8

      UniProtKB/TrEMBL
      G3V7S9
    Nucleotide Protein Strain
    Heading Accession and Version

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