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    RSPO2 R-spondin 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 482004, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RSPO2provided by VGNC
    Official Full Name
    R-spondin 2provided by VGNC
    Primary source
    VGNC:VGNC:45783
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (8873544..9022401, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (8550551..8728117, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (8823008..8971462, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (8627417..8772877, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (8745404..8896677, complement)

    Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098519 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC102154405 Neighboring gene eukaryotic translation initiation factor 3 subunit E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coat variation in the domestic dog is governed by variants in three genes. Cadieu E, et al. Science, 2009 Oct 2. PMID 19713490, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    R-spondin-2
    Names
    R-spondin 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051817.1 Reference ROS_Cfam_1.0

      Range
      8873544..9022401 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038684848.1 → XP_038540776.1  R-spondin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    2. XM_038684849.1 → XP_038540777.1  R-spondin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    3. XM_038684850.1 → XP_038540778.1  R-spondin-2 isoform X2

      Conserved Domains (2) summary
      pfam15913
      Location:1 → 74
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:78 → 131
      TSP1_spondin; Spondin-like TSP1 domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049273.1 Alternate UMICH_Zoey_3.1

      Range
      8627417..8772877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038493073.1 → XP_038349001.1  R-spondin-2 isoform X1

      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    2. XM_038493074.1 → XP_038349002.1  R-spondin-2 isoform X1

      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    3. XM_038493075.1 → XP_038349003.1  R-spondin-2 isoform X2

      Conserved Domains (2) summary
      pfam15913
      Location:1 → 74
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:78 → 131
      TSP1_spondin; Spondin-like TSP1 domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

      Range
      8745404..8896677 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038619232.1 → XP_038475160.1  R-spondin-2 isoform X1

      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    2. XM_038619233.1 → XP_038475161.1  R-spondin-2 isoform X1

      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    3. XM_038619234.1 → XP_038475162.1  R-spondin-2 isoform X2

      Conserved Domains (2) summary
      pfam15913
      Location:1 → 74
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:78 → 131
      TSP1_spondin; Spondin-like TSP1 domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

      Range
      8823008..8971462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038555332.1 → XP_038411260.1  R-spondin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    2. XM_038555333.1 → XP_038411261.1  R-spondin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    3. XM_038555334.1 → XP_038411262.1  R-spondin-2 isoform X2

      Conserved Domains (2) summary
      pfam15913
      Location:1 → 74
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:78 → 131
      TSP1_spondin; Spondin-like TSP1 domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8550551..8728117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005627871.4 → XP_005627928.1  R-spondin-2 isoform X1

      See identical proteins and their annotated locations for XP_005627928.1

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    2. XM_539125.6 → XP_539125.2  R-spondin-2 isoform X1

      See identical proteins and their annotated locations for XP_539125.2

      UniProtKB/TrEMBL
      A0A8C0QHB7, A0A8C0QN03, A0A8I3NC08
      Conserved Domains (2) summary
      pfam15913
      Location:40 → 141
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:145 → 198
      TSP1_spondin; Spondin-like TSP1 domain

    3. XM_022426651.2 → XP_022282359.2  R-spondin-2 isoform X2

      Conserved Domains (2) summary
      pfam15913
      Location:1 → 74
      Furin-like_2; Furin-like repeat, cysteine-rich
      pfam19028
      Location:78 → 131
      TSP1_spondin; Spondin-like TSP1 domain
    Nucleotide Protein
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