APLN apelin [Bos taurus (cattle)] - Gene

Summary

Official Symbol: APLNprovided by VGNC
Official Full Name: apelinprovided by VGNC
Primary source: VGNC:VGNC:26017
See related: BGD:BT10310; Ensembl:ENSBTAG00000019993
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	X	NC_037357.1 (13687958..13697147, complement)

Chromosome X - NC_037357.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results showed that serum Apelin-36 concentration decreased after parturition in dairy cow; alteration of Apelin-36 secretion after parturition may represent an endocrine adaptation in dairy cow during the lactating period.
Title: Serum Apelin-36 alteration in late pregnancy and early lactation of dairy cows and its association with negative energy balance markers.
APJ receptor in granulosa cells and both apelin and the APJ receptor in theca tissues are expressed in bovine ovary.
Title: Apelin and APJ receptor expression in granulosa and theca cells during different stages of follicular development in the bovine ovary: Involvement of apoptosis and hormonal regulation.
The data suggest that apelin/APJ system is involved in the mechanism regulating angiogenesis during follicle maturation as well as during corpora lutea formation and function in the bovine ovary.
Title: The expression of apelin and its receptor APJ during different physiological stages in the bovine ovary.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables apelin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apelin

Names: APJ endogenous ligand; apelin, AGTRL1 ligand; apelin; peptide ligand for APJ receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.