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    Kri1 KRI1 homolog [ Mus musculus (house mouse) ]

    Gene ID: 215194, updated on 5-Mar-2024

    Summary

    Official Symbol
    Kri1provided by MGI
    Official Full Name
    KRI1 homologprovided by MGI
    Primary source
    MGI:MGI:2384899
    See related
    Ensembl:ENSMUSG00000035047 AllianceGenome:MGI:2384899
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Is expressed in cervico-thoracic ganglion; tail dorsal root ganglion; and thymus primordium. Orthologous to human KRI1 (KRI1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 14.5), thymus adult (RPKM 12.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    9 A3; 9 7.76 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21184753..21199265, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21273457..21287969, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 16754 Neighboring gene STARR-seq mESC enhancer starr_23486 Neighboring gene kelch-like ECH-associated protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E8278 Neighboring gene sphingosine-1-phosphate receptor 5 Neighboring gene STARR-positive B cell enhancer mm9_chr9:21069491-21069792 Neighboring gene autophagy related 4D, cysteine peptidase Neighboring gene cyclin dependent kinase inhibitor 2D Neighboring gene adaptor protein complex AP-1, mu 2 subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145416.3NP_663391.2  protein KRI1 homolog

      See identical proteins and their annotated locations for NP_663391.2

      Status: VALIDATED

      Source sequence(s)
      BI989088, BQ557175, CJ069606, CK795617, CO426049, CO426749, CX562209
      Consensus CDS
      CCDS72201.1
      UniProtKB/Swiss-Prot
      Q8VDQ9
      UniProtKB/TrEMBL
      F6WIU1
      Related
      ENSMUSP00000039688.4, ENSMUST00000038671.10
      Conserved Domains (2) summary
      pfam05178
      Location:340410
      Kri1; KRI1-like family
      pfam12936
      Location:501589
      Kri1_C; KRI1-like family C-terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21184753..21199265 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)