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LOC8023133 DNA topoisomerase 2-alpha [ Ixodes scapularis (black-legged tick) ]

Gene ID: 8023133, updated on 10-May-2024

Summary

Gene symbol
LOC8023133
Gene description
DNA topoisomerase 2-alpha
See related
VectorBase:ISCP_030498; EnsemblRapid:LOC8023133
Gene type
protein coding
RefSeq status
MODEL
Organism
Ixodes scapularis
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
103 current ASM1692078v2 (GCF_016920785.2) Unplaced Scaffold NW_024609881.1 (122074870..122087604)
102 previous assembly Ixodes_scapularus_ComboLowHiFi (GCF_016920785.1) Unplaced Scaffold NW_024389252.1 (1141121..1154428, complement)

NW_024609881.1Genomic Context describing neighboring genes Neighboring gene 85/88 kDa calcium-independent phospholipase A2 Neighboring gene mismatch repair endonuclease PMS2 Neighboring gene epsin-2 Neighboring gene methyltransferase-like protein 23

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in sister chromatid segregation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ixodes scapularis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1692078v2

Genomic

  1. NW_024609881.1 Reference ASM1692078v2

    Range
    122074870..122087604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002399281.5XP_002399322.4  DNA topoisomerase 2-alpha

    UniProtKB/TrEMBL
    B7P0P1
    Related
    XP_002399322.4, XM_002399281.5
    Conserved Domains (1) summary
    PTZ00108
    Location:291402
    PTZ00108; DNA topoisomerase 2-like protein; Provisional