CDK5RAP2 CDK5 regulatory subunit associated protein 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CDK5RAP2provided by CGNC
Full Name: CDK5 regulatory subunit associated protein 2provided by CGNC
Primary source: CGNC:5260
See related: Ensembl:ENSGALG00010027929
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: EGFL5
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 40

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	17	NC_052548.1 (5170346..5248860, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	17	NC_052589.1 (4584202..4662679, complement)

Chromosome 17 - NC_052548.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calmodulin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables gamma-tubulin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables microtubule binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription cis-regulatory region binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in centriole replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chromosome segregation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in establishment of mitotic spindle orientation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in microtubule bundle formation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of centriole replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of microtubule polymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of mitotic cell cycle spindle assembly checkpoint	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in microtubule organizing center	IEA Inferred from Electronic Annotation more info	PubMed
located_in microtubule plus-end	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle pole	IEA Inferred from Electronic Annotation more info	PubMed
located_in pericentriolar material	IEA Inferred from Electronic Annotation more info	PubMed
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CDK5 regulatory subunit-associated protein 2

Names: EGF-like-domain, multiple 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

5170346..5248860 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040649272.2 → XP_040505206.1 CDK5 regulatory subunit-associated protein 2 isoform X2

UniProtKB/TrEMBL

A0A8V1AGH3

Related

ENSGALP00010041440.1, ENSGALT00010067698.1

Conserved Domains (2) summary

COG0419
Location:230 → 753

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:1583 → 1784

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040649271.2 → XP_040505205.1 CDK5 regulatory subunit-associated protein 2 isoform X1

UniProtKB/TrEMBL

A0A8V1AGH3, A0A8V1AIB8

Related

ENSGALP00010041447.1, ENSGALT00010067704.1

Conserved Domains (2) summary

COG0419
Location:230 → 753

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:1589 → 1823

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040649273.2 → XP_040505207.1 CDK5 regulatory subunit-associated protein 2 isoform X3

UniProtKB/TrEMBL

A0A8V1A6A0, A0A8V1AB60

Related

ENSGALP00010041445.1, ENSGALT00010067702.1

Conserved Domains (2) summary

COG0419
Location:97 → 620

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:1456 → 1690

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040649274.2 → XP_040505208.1 CDK5 regulatory subunit-associated protein 2 isoform X4

UniProtKB/TrEMBL

A0A8V1AB60

Conserved Domains (2) summary

COG0419
Location:1012 → 1546

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:112 → 474

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

4584202..4662679 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040685443.2 → XP_040541377.1 CDK5 regulatory subunit-associated protein 2 isoform X2

UniProtKB/TrEMBL

A0A8V1AGH3

Conserved Domains (2) summary

COG0419
Location:394 → 1048

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:262 → 659

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040685442.2 → XP_040541376.1 CDK5 regulatory subunit-associated protein 2 isoform X1

UniProtKB/TrEMBL

A0A8V1AGH3

Conserved Domains (2) summary

COG0419
Location:1291 → 1825

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:262 → 659

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040685444.2 → XP_040541378.1 CDK5 regulatory subunit-associated protein 2 isoform X3

UniProtKB/TrEMBL

A0A8V1AB60

Conserved Domains (2) summary

COG0419
Location:1158 → 1692

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:129 → 526

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_040685445.2 → XP_040541379.1 CDK5 regulatory subunit-associated protein 2 isoform X4

UniProtKB/TrEMBL

A0A8V1AB60

Conserved Domains (3) summary

COG0419
Location:1012 → 1546

SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]

COG1196
Location:1310 → 1544

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

TIGR02168
Location:14 → 368

SMC_prok_B; chromosome segregation protein SMC, common bacterial type