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DUSP2 dual specificity phosphatase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 718442, updated on 17-Aug-2024

Summary

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Official Symbol
DUSP2provided by VGNC
Official Full Name
dual specificity phosphatase 2provided by VGNC
Primary source
VGNC:VGNC:106150
See related
Ensembl:ENSMMUG00000049314
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
4
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (568411..571042, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (91949731..91952554, complement)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene adrenoceptor alpha 2B Neighboring gene astacin like metalloendopeptidase Neighboring gene uncharacterized LOC114671860 Neighboring gene uncharacterized LOC114671861 Neighboring gene StAR related lipid transfer domain containing 7 Neighboring gene uncharacterized LOC114671862

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    568411..571042 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001111118.4 → XP_001111118.4  dual specificity protein phosphatase 2

    UniProtKB/TrEMBL
    A0A5F7ZNZ7
    Related
    ENSMMUP00000066901.1, ENSMMUT00000097697.1
    Conserved Domains (2) summary
    cd01446
    Location:55 → 190
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
    cd14641
    Location:218 → 361
    DSP_DUSP2; dual specificity phosphatase domain of dual specificity protein phosphatase 2
Nucleotide Protein
Heading Accession and Version

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