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GRM2 glutamate metabotropic receptor 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 700214, updated on 17-Aug-2024

Summary

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Official Symbol
GRM2provided by VGNC
Official Full Name
glutamate metabotropic receptor 2provided by VGNC
Primary source
VGNC:VGNC:73286
Locus tag
EGK_11587
See related
Ensembl:ENSMMUG00000012005
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (107787490..107799612)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (90607982..90620044, complement)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene testis expressed 264, ER-phagy receptor Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC114676356 Neighboring gene IQ motif containing F6 Neighboring gene IQ motif containing F4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables group II metabotropic glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled glutamate receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metabotropic glutamate receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001265680.1 → NP_001252609.1  metabotropic glutamate receptor 2 precursor

    See identical proteins and their annotated locations for NP_001252609.1

    Status: PROVISIONAL

    Source sequence(s)
    JV667261
    UniProtKB/TrEMBL
    A0A1D5QTR5, A0A1D5RJV7, A0A8J8YHU3, F7H091, F7H092, G7ML50
    Related
    ENSMMUP00000015746.2, ENSMMUT00000016813.4
    Conserved Domains (4) summary
    cd06375
    Location:30 → 480
    PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
    pfam07562
    Location:498 → 546
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:567 → 591
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:566 → 819
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    107787490..107799612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015130559.2 → XP_014986045.2  metabotropic glutamate receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A1D5RJV7
    Related
    ENSMMUP00000051445.2, ENSMMUT00000057685.2
    Conserved Domains (4) summary
    cd06375
    Location:119 → 569
    PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
    pfam07562
    Location:587 → 635
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:656 → 680
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:655 → 908
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_015130560.2 → XP_014986046.2  metabotropic glutamate receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5RJV7
    Related
    ENSMMUP00000060601.2, ENSMMUT00000064975.2
    Conserved Domains (4) summary
    cd06375
    Location:119 → 569
    PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
    pfam07562
    Location:587 → 635
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:656 → 680
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:655 → 879
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_028843161.1 → XP_028698994.1  metabotropic glutamate receptor 2 isoform X3

    UniProtKB/TrEMBL
    A0A1D5QTR5, A0A1D5RJV7, A0A8J8YHU3, F7H091, F7H092, G7ML50
    Conserved Domains (4) summary
    cd06375
    Location:30 → 480
    PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
    pfam07562
    Location:498 → 546
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd14964
    Location:567 → 591
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:566 → 819
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein
Heading Accession and Version

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