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SMG1 SMG1 nonsense mediated mRNA decay associated PI3K related kinase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 693542, updated on 5-Mar-2024

Summary

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Official Symbol
SMG1provided by VGNC
Official Full Name
SMG1 nonsense mediated mRNA decay associated PI3K related kinaseprovided by VGNC
Primary source
VGNC:VGNC:99591
See related
Ensembl:ENSMMUG00000022441
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SMG1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
64
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (17647677..17759777, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (17961999..18074948, complement)

Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 1 Neighboring gene small nucleolar RNA U13 Neighboring gene histone chaperone ASF1-like Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane channel like 7 Neighboring gene uncharacterized LOC114674480 Neighboring gene coenzyme Q7, hydroxylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase SMG1
Names
serine/threonine-protein kinase SMG1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041773.1 Reference Mmul_10 Primary Assembly

    Range
    17647677..17759777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015125711.2 → XP_014981197.1  serine/threonine-protein kinase SMG1 isoform X2

    UniProtKB/TrEMBL
    H9F9J1
    Conserved Domains (4) summary
    cd05170
    Location:2120 → 2453
    PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
    pfam02260
    Location:3657 → 3686
    FATC; FATC domain
    pfam15785
    Location:630 → 1241
    SMG1; Serine/threonine-protein kinase smg-1
    pfam17229
    Location:31 → 139
    DUF5303; Region of unknown function (DUF5303)

  2. XM_015125710.2 → XP_014981196.1  serine/threonine-protein kinase SMG1 isoform X1

    UniProtKB/TrEMBL
    H9F9J1
    Conserved Domains (4) summary
    cd05170
    Location:2120 → 2453
    PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
    pfam02260
    Location:3658 → 3687
    FATC; FATC domain
    pfam15785
    Location:630 → 1241
    SMG1; Serine/threonine-protein kinase smg-1
    pfam17229
    Location:31 → 139
    DUF5303; Region of unknown function (DUF5303)

  3. XM_015125715.2 → XP_014981201.1  serine/threonine-protein kinase SMG1 isoform X4

    UniProtKB/TrEMBL
    A0A5F7ZLC3, H9F9J1
    Related
    ENSMMUP00000065979.1, ENSMMUT00000083643.1
    Conserved Domains (4) summary
    cd05170
    Location:2120 → 2425
    PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
    pfam02260
    Location:3630 → 3659
    FATC; FATC domain
    pfam15785
    Location:630 → 1241
    SMG1; Serine/threonine-protein kinase smg-1
    pfam17229
    Location:31 → 139
    DUF5303; Region of unknown function (DUF5303)

  4. XM_015125714.2 → XP_014981200.1  serine/threonine-protein kinase SMG1 isoform X3

    UniProtKB/TrEMBL
    F7ENF7
    Related
    ENSMMUP00000028725.3, ENSMMUT00000030691.4
    Conserved Domains (4) summary
    cd05170
    Location:2095 → 2428
    PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
    pfam02260
    Location:3633 → 3662
    FATC; FATC domain
    pfam15785
    Location:605 → 1216
    SMG1; Serine/threonine-protein kinase smg-1
    pfam17229
    Location:6 → 114
    DUF5303; Region of unknown function (DUF5303)

  5. XM_015125713.2 → XP_014981199.1  serine/threonine-protein kinase SMG1 isoform X3

    UniProtKB/TrEMBL
    F7ENF7
    Related
    ENSMMUP00000056613.2, ENSMMUT00000061354.2
    Conserved Domains (4) summary
    cd05170
    Location:2095 → 2428
    PIKKc_SMG1; Catalytic domain of Suppressor of Morphogenetic effect on Genitalia-1
    pfam02260
    Location:3633 → 3662
    FATC; FATC domain
    pfam15785
    Location:605 → 1216
    SMG1; Serine/threonine-protein kinase smg-1
    pfam17229
    Location:6 → 114
    DUF5303; Region of unknown function (DUF5303)
Nucleotide Protein
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