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Zfp579 zinc finger protein 579 [ Mus musculus (house mouse) ]

Gene ID: 68490, updated on 30-Apr-2024

Summary

Official Symbol
Zfp579provided by MGI
Official Full Name
zinc finger protein 579provided by MGI
Primary source
MGI:MGI:1915740
See related
Ensembl:ENSMUSG00000051550 AllianceGenome:MGI:1915740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf579; 1110003A17Rik
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Is expressed in metencephalon part of 4th ventricle choroid plexus. Orthologous to human ZNF579 (zinc finger protein 579). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 40.0), whole brain E14.5 (RPKM 32.1) and 27 other tissues See more
Orthologs
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Genomic context

See Zfp579 in Genome Data Viewer
Location:
7 A1; 7 2.88 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4995851..4999100, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4992852..4996101, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene SH3-binding domain kinase family, member 2 Neighboring gene SH3 domain binding kinase family, member 3 Neighboring gene predicted gene, 53351 Neighboring gene Flt3 interacting zinc finger protein 1 Neighboring gene STARR-seq mESC enhancer starr_17950

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026741.2NP_081017.1  zinc finger protein 579

    See identical proteins and their annotated locations for NP_081017.1

    Status: VALIDATED

    Source sequence(s)
    BC048385, CX205499
    Consensus CDS
    CCDS39744.1
    UniProtKB/Swiss-Prot
    Q80VM4
    Related
    ENSMUSP00000104212.2, ENSMUST00000108572.2
    Conserved Domains (4) summary
    COG5048
    Location:45107
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:295317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:6085
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    4995851..4999100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540335.4XP_006540398.1  zinc finger protein 579 isoform X1

    See identical proteins and their annotated locations for XP_006540398.1

    UniProtKB/Swiss-Prot
    Q80VM4
    Conserved Domains (4) summary
    COG5048
    Location:45107
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:295317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:6085
    zf-H2C2_2; Zinc-finger double domain